Cell Biology Antibodies 13
Anti-TPCN2 Antibody (CAB17271)
- SKU:
- CAB17271
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Antibody Name: | Anti-TPCN2 Antibody (CAB17271) |
Antibody SKU: | CAB17271 |
Antibody Size: | 50µL, 100µL |
Application: | Western blotting |
Reactivity: | Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-85 of human TPCN2 (NP_620714.2). |
Application: | Western blotting |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse |
Positive Samples: | Mouse heart |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-85 of human TPCN2 (NP_620714.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LLGG ARGG GGDW PAGL TTYR SIQV GPGA AARW DLCI DQAV VFIE DAIQ YRSI NHRV DASS MWLY RRYY SNVC QRT |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 85KDa |
Synonyms: | TPCN2, SHEP10, TPC2 |
Background: | This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation. |
Western blot analysis of extracts of Mouse heart, using TPCN2 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 300s. |