Epigenetics & Nuclear Signaling Antibodies 2

Anti-TP53RK Antibody (CAB14952)

(No reviews yet) Write a Review
SKU:
CAB14952

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TP53RK Antibody
Antibody SKU:CAB14952
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TP53RK (NP_291028.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, BxPC-3, 293T, HeLa, Jurkat, Mouse thymus, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TP53RK (NP_291028.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAAA RATT PADG EEPA PEAE ALAA ARER SSRF LSGL ELVK QGAE ARVF RGRF QGRA AVIK HRFP KGYR HPAL EARL GRRR TVQE ARAL LRCR RAGI SAPV VFFV DYAS NCLY MEEI EGSV TVRD YIQS TMET EKTP QGLS NLAK TIGQ VLAR MHDE DLIH GDLT TSNM LLKP PLEQ LNIV LIDF GLSF ISAL PEDK GVDL YVLE KAFL STHP NTET VFEA FLKS YSTS SKKA RPVL KKLD EVRL RGRK RSMV G
Gene ID:112858
Uniprot:Q96S44
Cellular Location:Nucleus
Calculated MW:28kDa
Observed MW:28kDa
Synonyms:TP53RK, BUD32, C20orf64, Nori-2, Nori-2p, PRPK, dJ101A2
Background:
UniProt Protein Function:PRPK: Protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation. Belongs to the protein kinase superfamily.
UniProt Protein Details:

Protein type:Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, Other; EC 2.7.11.1; Other group; Bud32 family

Chromosomal Location of Human Ortholog: 20q13.2

Cellular Component: cytosol; nucleoplasm; nucleus

Molecular Function:p53 binding; protein binding; protein serine/threonine kinase activity

Biological Process: protein amino acid phosphorylation

UniProt Code:Q96S44
NCBI GenInfo Identifier:26398348
NCBI Gene ID:112858
NCBI Accession:Q96S44.2
UniProt Secondary Accession:Q96S44,Q3T977, Q5JZ01, Q6NZ60, Q96FM7, Q9NQE6, B3KU44
UniProt Related Accession:Q96S44
Molecular Weight:28,160 Da
NCBI Full Name:TP53-regulating kinase
NCBI Synonym Full Names:TP53 regulating kinase
NCBI Official Symbol:TP53RK  
NCBI Official Synonym Symbols:PRPK; BUD32; Nori-2; Nori-2p; dJ101A2; C20orf64  
NCBI Protein Information:TP53-regulating kinase
UniProt Protein Name:TP53-regulating kinase
UniProt Synonym Protein Names:Atypical serine/threonine protein kinase TP53RK; EKC/KEOPS complex subunit TP53RK (EC:3.6.-.-); Nori-2; p53-related protein kinase
Protein Family:TP53-regulating kinase
UniProt Gene Name:TP53RK  
UniProt Entry Name:PRPK_HUMAN
Anti-TP53RK Antibody (CAB14952)Western blot analysis of extracts of various cell lines, using TP53RK antibody (CAB14952) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
View AllClose

Additional Information

Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
View AllClose

Related Products