Cell Biology Antibodies 9

Anti-TOMM34 Antibody (CAB4467)

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SKU:
CAB4467
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
TOMM34
Synonyms:
HTOM34P
Synonyms:
TOM34
Synonyms:
URCC3
Research Area:
Cell Biology

Description

Product Name:TOMM34 Rabbit pAb
Product Code:CAB4467
Size:20uL, 50uL, 100uL
Synonyms:TOMM34, HTOM34P, TOM34, URCC3
Applications:WB, IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human TOMM34 (NP_006800.2).
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:293T, A-431, HeLa, HepG2, BT-474, SW620, Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human TOMM34 (NP_006800.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAPK FPDS VEEL RAAG NESF RNGQ YAEA SALY GRAL RVLQ AQGS SDPE EESV LYSN RAAC HLKD GNCR DCIK DCTS ALAL VPFS IKPL LRRA SAYE ALEK YPMA YVDY KTVL QIDD NVTS AVEG INRM TRAL MDSL GPEW RLKL PSIP LVPV SAQK RWNS LPSE NHKE MAKS KSKE TTAT KNRV PSAG DVEK ARVL KEEG NELV KKGN HKKA IEKY SESL LCSN LESA TYSN RALC YLVL KQYT EAVK DCTE ALKL DGKN VKAF YRRA QAHK ALKD YKSS FADI SNLL QIEP RNGP AQKL RQEV KQNL H
Gene ID:10953
Uniprot:Q15785
Cellular Location:Cytoplasm, Cytoplasmic side, Mitochondrion outer membrane, Peripheral membrane protein
Calculated MW:34kDa
Observed MW:35kDa
UniProt Protein Function:TOMM34: Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state. Belongs to the Tom34 family.
UniProt Protein Details:

Protein type:Chaperone; Mitochondrial

Chromosomal Location of Human Ortholog: -

Cellular Component: cytoplasm; integral to membrane; membrane; mitochondrial outer membrane; nucleoplasm; nucleus

Molecular Function:heat shock protein binding; protein binding

Biological Process: protein targeting to mitochondrion

NCBI Summary:The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats. [provided by RefSeq, Jul 2008]
UniProt Code:Q15785
NCBI GenInfo Identifier:24212065
NCBI Gene ID:10953
NCBI Accession:Q15785.2
UniProt Secondary Accession:Q15785,Q53GH9, Q6IBN7, Q9NTZ3,
UniProt Related Accession:Q15785
Molecular Weight:34,559 Da
NCBI Full Name:Mitochondrial import receptor subunit TOM34
NCBI Synonym Full Names:translocase of outer mitochondrial membrane 34
NCBI Official Symbol:TOMM34  
NCBI Official Synonym Symbols:TOM34; URCC3; HTOM34P  
NCBI Protein Information:mitochondrial import receptor subunit TOM34
UniProt Protein Name:Mitochondrial import receptor subunit TOM34
UniProt Synonym Protein Names:Translocase of outer membrane 34 kDa subunit
Protein Family:Mitochondrial import receptor
UniProt Gene Name:TOMM34  
UniProt Entry Name:TOM34_HUMAN
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