Cell Biology Antibodies 13
Anti-TOM1L1 Antibody (CAB17602)
(No reviews yet)
Write a Review
- SKU:
- CAB17602
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TOM1L1 Antibody |
| Antibody SKU: | CAB17602 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of Human TOM1L1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HT-29, SGC-7901, Mouse kidney, Rat kidney |
| Immunogen: | A synthetic peptide of Human TOM1L1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10040 |
| Uniprot: | O75674 |
| Cellular Location: | |
| Calculated MW: | 38kDa/44kDa/52kDa |
| Observed MW: | 53kDa |
 | Western blot - TOM1L1 Polyclonal Antibody (CAB17602) |
| Synonyms: | SRCASM, TOM1L1 |
| Background: |
| UniProt Protein Function: | Srcasm: an adapter protein that is a src-family kinase substrate. When phosphorylated, it binds src-family kinases and targets them for lysosomal-dependent degradation. EGF triggers a transient association of phosphorylated Srcasm with EGFR via Grb2 and Shc initiating the endocytosis of the ligand-receptor complex. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. Involved in multivesicular body (MVB) formation, viral egress from the cell, and cytokinesis. Belongs to the TOM1 family. Interacts with FYN, GRB2 and PIK3R1 when phosphorylated. The PTAP sequence in the GAT domain and the PSAP sequence in the C-terminal region are responsible for its interaction with the UEV domain of Tsg101, a component of the ESCRT-1 complex. Localizes to the multivesicular body (MVB) that is involved in targeting endosomal proteins for lysosomal degradation. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 17q23.2 Cellular Component: cytoplasm; cytosol; endosome; lysosome Molecular Function:clathrin binding; protein binding; protein kinase binding; ubiquitin binding Biological Process: activation of protein kinase activity; negative regulation of mitosis; positive regulation of protein amino acid autophosphorylation; signal transduction |
| UniProt Code: | O75674 |
| NCBI GenInfo Identifier: | 215273903 |
| NCBI Gene ID: | 10040 |
| NCBI Accession: | O75674.2 |
| UniProt Secondary Accession: | O75674,Q53G06, Q8N749, B7Z9E2, |
| UniProt Related Accession: | O75674 |
| Molecular Weight: | 44,334 Da |
| NCBI Full Name: | TOM1-like protein 1 |
| NCBI Synonym Full Names: | target of myb1 like 1 membrane trafficking protein |
| NCBI Official Symbol: | TOM1L1 |
| NCBI Official Synonym Symbols: | SRCASM |
| NCBI Protein Information: | TOM1-like protein 1 |
| UniProt Protein Name: | TOM1-like protein 1 |
| UniProt Synonym Protein Names: | Src-activating and signaling molecule protein; Target of Myb-like protein 1 |
| Protein Family: | TOM1-like protein |
| UniProt Gene Name: | TOM1L1 |
| UniProt Entry Name: | TM1L1_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a