Cell Biology Antibodies 11
Anti-TNS3 Antibody (CAB7991)
- SKU:
- CAB7991
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | TNS3 Rabbit Polyclonal Antibody |
Antibody SKU: | CAB7991 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TNS3 (NP_073585.8). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | A-549 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TNS3 (NP_073585.8). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MEEG HGLD LTYI TERI IAVS FPAG CSEE SYLH NLQE VTRM LKSK HGDN YLVL NLSE KRYD LTKL NPKI MDVG WPEL HAPP LDKM CTIC KAQE SWLN SNLQ HVVV IHCR GGKG RIGV VISS YMHF TNVS ASAD QALD RFAM KKFY DDKV SALM QPSQ KRYV QFLS GLLS GSVK MNAS PLFL HFVI LHGT PNFD TGGV CRPF LKLY QAMQ PVYT SGIY NVGP ENPS RICI VIEP AQLL KGDV |
Gene ID: | 64759 |
Uniprot: | Q68CZ2 |
Cellular Location: | Cell junction, focal adhesion |
Calculated MW: | 28kDa/43kDa/129kDa/155kDa |
Observed MW: | 190kDa |
Synonyms: | TNS3, TEM6, TENS1, tensin-3 |
Background: |
UniProt Protein Function: | May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development. |
UniProt Code: | Q68CZ2 |
NCBI GenInfo Identifier: | 65288071 |
NCBI Gene ID: | 64759 |
NCBI Accession: | NP_073585.8 |
UniProt Secondary Accession: | Q68CZ2,Q6IPQ2, Q8IZW7, Q8NAD0, Q96PE0, Q96S48, B2RNV1 |
UniProt Related Accession: | Q68CZ2 |
Molecular Weight: | 28,043 Da |
NCBI Full Name: | tensin-3 |
NCBI Synonym Full Names: | tensin 3 |
NCBI Official Symbol: | TNS3 |
NCBI Official Synonym Symbols: | TEM6; TENS1 |
NCBI Protein Information: | tensin-3 |
UniProt Protein Name: | Tensin-3 |
UniProt Synonym Protein Names: | Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6 |
Protein Family: | Tensin |
UniProt Gene Name: | TNS3 |
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