Cell Biology Antibodies 13
Anti-TMX2 Antibody (CAB17148)
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- SKU:
- CAB17148
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TMX2 Antibody |
| Antibody SKU: | CAB17148 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 128-296 of human TMX2 (NP_057043.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, HeLa, HepG2, A-549, Mouse liver, Mouse brain, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 128-296 of human TMX2 (NP_057043.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KPPL YMGP EYIK YFND KTID EELE RDKR VTWI VEFF ANWS NDCQ SFAP IYAD LSLK YNCT GLNF GKVD VGRY TDVS TRYK VSTS PLTK QLPT LILF QGGK EAMR RPQI DKKG RAVS WTFS EENV IREF NLNE LYQR AKKL SKAG DNIP EEQP VAST PTTV SDGE NKKD K |
| Gene ID: | 51075 |
| Uniprot: | Q9Y320 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 38kDa |
 | Western blot - TMX2 Rabbit pAb (CAB17148) |
| Synonyms: | TMX2, CGI-31, PDIA12, PIG26, TXNDC14 |
| Background: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. |
| UniProt Protein Function: | TXNDC14: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11cen-q22.3 Cellular Component: cell; integral to membrane Biological Process: cell redox homeostasis |
| UniProt Code: | Q9Y320 |
| NCBI GenInfo Identifier: | 221136993 |
| NCBI Gene ID: | 51075 |
| NCBI Accession: | NP_001137484.1 |
| UniProt Secondary Accession: | Q9Y320,Q53G73, Q561W0, Q5J7Q7, Q8NBP9, Q9H3L1, B7Z4R4 |
| UniProt Related Accession: | Q9Y320 |
| Molecular Weight: | 29,642 Da |
| NCBI Full Name: | thioredoxin-related transmembrane protein 2 isoform 2 |
| NCBI Synonym Full Names: | thioredoxin related transmembrane protein 2 |
| NCBI Official Symbol: | TMX2 |
| NCBI Official Synonym Symbols: | PIG26; CGI-31; PDIA12; TXNDC14 |
| NCBI Protein Information: | thioredoxin-related transmembrane protein 2 |
| UniProt Protein Name: | Thioredoxin-related transmembrane protein 2 |
| UniProt Synonym Protein Names: | Cell proliferation-inducing gene 26 protein; Thioredoxin domain-containing protein 14 |
| Protein Family: | Thioredoxin-related transmembrane protein |
| UniProt Gene Name: | TMX2 |
| UniProt Entry Name: | TMX2_HUMAN |
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