Cell Biology Antibodies 9
Anti-TMSB4X Antibody (CAB5438)
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- SKU:
- CAB5438
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TMSB4X Antibody |
| Antibody SKU: | CAB5438 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-44 of human TMSB4X (NP_066932.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-44 of human TMSB4X (NP_066932.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSDK PDMA EIEK FDKS KLKK TETQ EKNP LPSK ETIE QEKQ AGES |
| Gene ID: | 7114 |
| Uniprot: | P62328 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 5kDa |
| Observed MW: | Refer to figures |
| Synonyms: | TMSB4X, FX, PTMB4, TB4X, TMSB4 |
| Background: | This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. |
| UniProt Protein Function: | TMSB4X: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: Xq21.3-q22 Cellular Component: cytoskeleton; extracellular region Molecular Function:actin monomer binding; protein binding Biological Process: platelet activation; platelet degranulation; sequestering of actin monomers; actin filament organization; blood coagulation |
| NCBI Summary: | This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P62328 |
| NCBI GenInfo Identifier: | 78103211 |
| NCBI Gene ID: | 7114 |
| NCBI Accession: | P62328.2 |
| UniProt Secondary Accession: | P62328,P01253, P01254, Q546P5, Q63576, Q9UE55, |
| UniProt Related Accession: | P62328 |
| Molecular Weight: | 44 |
| NCBI Full Name: | Thymosin beta-4 |
| NCBI Synonym Full Names: | thymosin beta 4, X-linked |
| NCBI Official Symbol: | TMSB4X |
| NCBI Official Synonym Symbols: | FX; TB4X; PTMB4; TMSB4 |
| NCBI Protein Information: | thymosin beta-4; t beta-4; prothymosin beta-4; thymosin, beta 4, X chromosome |
| UniProt Protein Name: | Thymosin beta-4 |
| UniProt Synonym Protein Names: | FxHematopoietic system regulatory peptideAlternative name(s):Seraspenide |
| Protein Family: | Thymosin |
| UniProt Gene Name: | TMSB4X |
| UniProt Entry Name: | TYB4_HUMAN |
 | Immunofluorescence analysis of HeLa cells using TMSB4X antibody (CAB5438). Blue: DAPI for nuclear staining. |
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