Cell Biology Antibodies 4

Anti-TMPRSS5 Antibody (CAB14307)

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SKU:
CAB14307
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TMPRSS5 Antibody
Antibody SKU:CAB14307
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 70-360 of human TMPRSS5 (NP_001275680.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-87MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 70-360 of human TMPRSS5 (NP_001275680.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PISG TLQD EEIT LSCS EASA EEAL LPAL PKTV SFRI NSED FLLE AQVR DQPR WLLV CHEG WSPA LGLQ ICWS LGHL RLTH HKGV NLTD IKLN SSQE FAQL SPRL GGFL EEAW QPRN NCTS GQVV SLRC SECG ARPL ASRI VGGQ SVAP GRWP WQAS VALG FRHT CGGS VLAP RWVV TAAH CMHS FRLA RLSS WRVH AGLV SHSA VRPH QGAL VERI IPHP LYSA QNHD YDVA LLRL QTAL NFSD TVGA VCLP AKEQ HFPK GSRC WVSG WGHT HPSH TYSS DMLQ DTVV PLF
Gene ID:80975
Uniprot:Q9H3S3
Cellular Location:Cell membrane, Single-pass type II membrane protein
Calculated MW:49kDa
Observed MW:50kDa
Synonyms:TMPRSS5, SPINESIN
Background:This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:TMPRSS5: May play a role in hearing. Defects in TMPRSS5 may be a cause of deafness. Belongs to the peptidase S1 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; EC 3.4.21.-; Protease

Chromosomal Location of Human Ortholog: 11q

Cellular Component: plasma membrane

Molecular Function:peptidase activity

Biological Process: proteolysis

NCBI Summary:This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
UniProt Code:Q9H3S3
NCBI GenInfo Identifier:296452845
NCBI Gene ID:80975
NCBI Accession:Q9H3S3.2
UniProt Related Accession:Q9H3S3
Molecular Weight:49,560 Da
NCBI Full Name:Transmembrane protease serine 5
NCBI Synonym Full Names:transmembrane protease, serine 5
NCBI Official Symbol:TMPRSS5  
NCBI Official Synonym Symbols:SPINESIN  
NCBI Protein Information:transmembrane protease serine 5
UniProt Protein Name:Transmembrane protease serine 5
UniProt Synonym Protein Names:Spinesin
Protein Family:Transmembrane protease serine
UniProt Gene Name:TMPRSS5  
UniProt Entry Name:TMPS5_HUMAN
Anti-TMPRSS5 Antibody (CAB14307)Western blot analysis of extracts of U-87MG cells, using TMPRSS5 antibody (CAB14307) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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