Cell Cycle Antibodies 2

Anti-TMPRSS11A Antibody (CAB8605)

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SKU:
CAB8605
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle

Description

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Antibody Name:Anti-TMPRSS11A Antibody
Antibody SKU:CAB8605
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, A-549, SW620, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SASF QPNL TVHI TGFG ALYY GGES QNDL REAR VKII SDDV CKQP QVYG NDIK PGMF CAGY MEGI YDAC RGDS GGPL VTRD LKDT WYLI GIVS WGDN CGQK DKPG VYTQ VTYY RNWI ASKT GI
Gene ID:339967
Uniprot:Q6ZMR5
Cellular Location:Membrane, Single-pass type II membrane protein
Calculated MW:47kDa
Observed MW:48kDa
Synonyms:TMPRSS11A, ECRG1
Background:
UniProt Protein Function:TMPRSS11A: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; EC 3.4.21.-; Protease

Chromosomal Location of Human Ortholog: 4q13.2

Cellular Component: integral to plasma membrane; extracellular region

Molecular Function:serine-type endopeptidase activity

Biological Process: proteolysis; cell cycle

UniProt Code:Q6ZMR5
NCBI GenInfo Identifier:167466252
NCBI Gene ID:339967
NCBI Accession:NP_001107859.1
UniProt Secondary Accession:Q6ZMR5,Q2NKI9, Q6JE90, Q7RTY4, Q86TK8, J3KNQ8,
UniProt Related Accession:Q6ZMR5
Molecular Weight:47,254 Da
NCBI Full Name:transmembrane protease serine 11A isoform 2
NCBI Synonym Full Names:transmembrane protease, serine 11A
NCBI Official Symbol:TMPRSS11A  
NCBI Official Synonym Symbols:ECRG1  
NCBI Protein Information:transmembrane protease serine 11A
UniProt Protein Name:Transmembrane protease serine 11A
UniProt Synonym Protein Names:Airway trypsin-like protease 1; Epidermal type-II transmembrane serine protease; Esophageal cancer-susceptibility gene 1 protein
UniProt Gene Name:TMPRSS11A  
UniProt Entry Name:TM11A_HUMAN
Anti-TMPRSS11A Polyclonal Antibody (CAB8605)Western blot analysis of extracts of various cell lines, using TMPRSS11A antibody (CAB8605) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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