Cell Biology Antibodies 10
Anti-TMOD4 Antibody (CAB6772)
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- SKU:
- CAB6772
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TMOD4 Antibody |
| Antibody SKU: | CAB6772 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human TMOD4 (NP_037485.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human TMOD4 (NP_037485.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSSY QKEL EKYR DIDE DEIL RTLS PEEL EQLD CELQ EMDP ENML LPAG LRQR DQTK KSPT GPLD REAL LQYL EQQA LEVK ERDD LVPF TGEK KGKP YIQP KREI PAEE QITL EPEL EEAL AHAT DAEM CDIA AILD MYTL MSNK QYYD ALCS GEIC NTEG ISSV VQPD KYKP VPDE PPNP TNIE EILK RVRS NDKE LEEV NLNN IQDI PIPM LSEL CEAM KANT YVRS FSLV ATRS GDPI ANAV ADML RENR SLQS LNIE SNFI SSTG LMAV LKAV RENA TLTE LRVD NQRQ WPGD AVEM EMAT VLEQ CPSI VRFG YHFT QQGP RARA AQAM TRNN ELRR QQKK R |
| Gene ID: | 29765 |
| Uniprot: | Q9NZQ9 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 31kDa/39kDa |
| Observed MW: | 39kDa |
| Synonyms: | TMOD4, SK-TMOD |
| Background: |
| UniProt Protein Function: | TMOD4: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. Belongs to the tropomodulin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q12 Cellular Component: striated muscle thin filament Biological Process: actin filament organization; muscle contraction; myofibril assembly |
| UniProt Code: | Q9NZQ9 |
| NCBI GenInfo Identifier: | 23396885 |
| NCBI Gene ID: | 29765 |
| NCBI Accession: | Q9NZQ9.1 |
| UniProt Secondary Accession: | Q9NZQ9,Q5JR83, Q8WVL3, Q9UKH2, B7Z6N9, |
| UniProt Related Accession: | Q9NZQ9 |
| Molecular Weight: | 31,643 Da |
| NCBI Full Name: | Tropomodulin-4 |
| NCBI Synonym Full Names: | tropomodulin 4 |
| NCBI Official Symbol: | TMOD4 |
| NCBI Official Synonym Symbols: | SK-TMOD |
| NCBI Protein Information: | tropomodulin-4 |
| UniProt Protein Name: | Tropomodulin-4 |
| UniProt Synonym Protein Names: | Skeletal muscle tropomodulin; Sk-Tmod |
| Protein Family: | Tropomodulin |
| UniProt Gene Name: | TMOD4 |
| UniProt Entry Name: | TMOD4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TMOD4 antibody (CAB6772) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using TMOD4 antibody (CAB6772) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using TMOD4 antibody (CAB6772). Blue: DAPI for nuclear staining. |
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