Anti-TMOD2 Antibody (CAB19770)
- SKU:
- CAB19770
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- N-TMOD
- Synonyms:
- NTMOD
- Research Area:
- Cell Biology
Description
| Product Name: | TMOD2 Rabbit mAb |
| Product Code: | CAB19770 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | N-TMOD, NTMOD |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human TMOD2 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, U-251MG, Mouse testis, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human TMOD2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 29767 |
| Uniprot: | Q9NZR1 |
| Calculated MW: | 40kDa |
| Observed MW: | 40KDa |
| UniProt Protein Function: | TMOD2: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. Belongs to the tropomodulin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: striated muscle thin filament Biological Process: actin filament organization; muscle contraction; myofibril assembly; nervous system development |
| NCBI Summary: | This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9NZR1 |
| NCBI GenInfo Identifier: | 23396886 |
| NCBI Gene ID: | 29767 |
| NCBI Accession: | Q9NZR1.1 |
| UniProt Secondary Accession: | Q9NZR1,B4DEW6, |
| UniProt Related Accession: | Q9NZR1 |
| Molecular Weight: | 35,648 Da |
| NCBI Full Name: | Tropomodulin-2 |
| NCBI Synonym Full Names: | tropomodulin 2 |
| NCBI Official Symbol: | TMOD2 |
| NCBI Official Synonym Symbols: | NTMOD; N-TMOD |
| NCBI Protein Information: | tropomodulin-2 |
| UniProt Protein Name: | Tropomodulin-2 |
| UniProt Synonym Protein Names: | Neuronal tropomodulin; N-Tmod |
| Protein Family: | Tropomodulin |
| UniProt Gene Name: | TMOD2 |
| UniProt Entry Name: | TMOD2_HUMAN |
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