Developmental Biology

Anti-TMEM176B Antibody (CAB16118)

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SKU:
CAB16118
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-TMEM176B Antibody
Antibody SKU:CAB16118
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 148-208 of human TMEM176B (NP_054739.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-87MG, Mouse lung, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 148-208 of human TMEM176B (NP_054739.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NSFI WQTE PFLY IDTV CDRS DPVF PTTG YRWM RRSQ ENQW QKEE CRAY MQML RKLF TAIR A
Gene ID:28959
Uniprot:Q3YBM2
Cellular Location:Multi-pass membrane protein, Nucleus membrane
Calculated MW:25kDa/29kDa
Observed MW:29kDa
Synonyms:TMEM176B, LR8, MS4B2
Background:
UniProt Protein Function:TMEM176B: May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells. Belongs to the TMEM176 family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: integral to membrane; nuclear membrane

Biological Process: cell differentiation; organ morphogenesis

UniProt Code:Q3YBM2
NCBI GenInfo Identifier:156416022
NCBI Gene ID:28959
NCBI Accession:NP_001094784.1
UniProt Secondary Accession:Q3YBM2,Q5BJI2, Q9BT42, Q9Y609, B2RDK2, D3DWZ7, E9PAV4
UniProt Related Accession:Q3YBM2
Molecular Weight:
NCBI Full Name:transmembrane protein 176B isoform b
NCBI Synonym Full Names:transmembrane protein 176B
NCBI Official Symbol:TMEM176B  
NCBI Official Synonym Symbols:LR8; MS4B2  
NCBI Protein Information:transmembrane protein 176B
UniProt Protein Name:Transmembrane protein 176B
UniProt Synonym Protein Names:Protein LR8
Protein Family:Transmembrane protein
UniProt Gene Name:TMEM176B  
UniProt Entry Name:T176B_HUMAN
Anti-TMEM176B Antibody (CAB16118)Western blot analysis of extracts of various cell lines, using TMEM176B antibody (CAB16118) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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