Signal Transduction Antibodies 2
Anti-TMEM100 Antibody (CAB16653)
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- SKU:
- CAB16653
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-TMEM100 Antibody |
| Antibody SKU: | CAB16653 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, SH-SY5Y, Mouse lung |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ELSC YRCI IPFA VVVF IAGI VVTA VAYS FNSH GSII SIFG LVVL SSGL FLLA SSAL CWKV RQRS KKAK RRES QTAL VANQ RSLF A |
| Gene ID: | 55273 |
| Uniprot: | Q9NV29 |
| Cellular Location: | |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | TMEM100 |
| Background: |
| UniProt Protein Function: | TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level)Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17q22Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; plasma membrane; perikaryonBiological Process: BMP signaling pathway; Notch signaling pathway; positive regulation of endothelial cell differentiation; in utero embryonic development; protein kinase B signaling cascade; angiogenesis; vasculogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NV29 |
| NCBI GenInfo Identifier: | 153792480 |
| NCBI Gene ID: | 55273 |
| NCBI Accession: | NP_001093110.1 |
| UniProt Secondary Accession: | Q9NV29,Q96FZ0, D3DTY7, I3L214 |
| UniProt Related Accession: | Q9NV29 |
| Molecular Weight: | 14,386 Da |
| NCBI Full Name: | transmembrane protein 100 |
| NCBI Synonym Full Names: | transmembrane protein 100 |
| NCBI Official Symbol: | TMEM100 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | transmembrane protein 100 |
| UniProt Protein Name: | Transmembrane protein 100 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM100 |
| UniProt Entry Name: | TM100_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TMEM100 antibody (CAB16653) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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