Signal Transduction Antibodies 2

Anti-TMEM100 Antibody (CAB16653)

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SKU:
CAB16653
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TMEM100 Antibody
Antibody SKU:CAB16653
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:293T, SH-SY5Y, Mouse lung
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ELSC YRCI IPFA VVVF IAGI VVTA VAYS FNSH GSII SIFG LVVL SSGL FLLA SSAL CWKV RQRS KKAK RRES QTAL VANQ RSLF A
Gene ID:55273
Uniprot:Q9NV29
Cellular Location:
Calculated MW:14kDa
Observed MW:14kDa
Synonyms:TMEM100
Background:
UniProt Protein Function:TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level)Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17q22Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane; plasma membrane; perikaryonBiological Process: BMP signaling pathway; Notch signaling pathway; positive regulation of endothelial cell differentiation; in utero embryonic development; protein kinase B signaling cascade; angiogenesis; vasculogenesis
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9NV29
NCBI GenInfo Identifier:153792480
NCBI Gene ID:55273
NCBI Accession:NP_001093110.1
UniProt Secondary Accession:Q9NV29,Q96FZ0, D3DTY7, I3L214
UniProt Related Accession:Q9NV29
Molecular Weight:14,386 Da
NCBI Full Name:transmembrane protein 100
NCBI Synonym Full Names:transmembrane protein 100
NCBI Official Symbol:TMEM100  
NCBI Official Synonym Symbols:
NCBI Protein Information:transmembrane protein 100
UniProt Protein Name:Transmembrane protein 100
UniProt Synonym Protein Names:
Protein Family:Transmembrane protein
UniProt Gene Name:TMEM100  
UniProt Entry Name:TM100_HUMAN
Anti-TMEM100 Antibody (CAB16653)Western blot analysis of extracts of various cell lines, using TMEM100 antibody (CAB16653) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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