Cell Biology Antibodies 15
Anti-TMBIM1 Antibody (CAB8249)
- SKU:
- CAB8249
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Description
| Antibody Name: | Anti-TMBIM1 Antibody |
| Antibody SKU: | CAB8249 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TMBIM1 (NP_071435.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-251MG |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TMBIM1 (NP_071435.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSNP SAPP PYED RNPL YPGP PPPG GYGQ PSVL PGGY PAYP GYPQ PGYG HPAG YPQP MPPT HPMP MNYG PGHG YDGE ERAV SDSF GPGE WDDR KVRH TFIR |
| Gene ID: | 64114 |
| Uniprot: | Q969X1 |
| Cellular Location: | Endosome membrane, Lysosome membrane, Membrane, Multi-pass membrane protein |
| Calculated MW: | 34kDa |
| Observed MW: | 35kDa |
| Synonyms: | TMBIM1, LFG3, MST100, MSTP100, PP1201, RECS1 |
| Background: |
| UniProt Protein Function: | TMBIM1: Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. Belongs to the BI1 family. LFG subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 2q35 Cellular Component: endosome membrane; Golgi apparatus; lysosomal membrane Molecular Function:death receptor binding Biological Process: negative regulation of catalytic activity |
| UniProt Code: | Q969X1 |
| NCBI GenInfo Identifier: | 93117549 |
| NCBI Gene ID: | 64114 |
| NCBI Accession: | Q969X1.2 |
| UniProt Secondary Accession: | Q969X1,Q8N1R3, Q8TAM3, Q96K13, B3KQY6, |
| UniProt Related Accession: | Q969X1 |
| Molecular Weight: | 34,607 Da |
| NCBI Full Name: | Protein lifeguard 3 |
| NCBI Synonym Full Names: | transmembrane BAX inhibitor motif containing 1 |
| NCBI Official Symbol: | TMBIM1 |
| NCBI Official Synonym Symbols: | LFG3; RECS1; MST100; PP1201; MSTP100 |
| NCBI Protein Information: | protein lifeguard 3 |
| UniProt Protein Name: | Protein lifeguard 3 |
| UniProt Synonym Protein Names: | Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1 |
| Protein Family: | Protein lifeguard |
| UniProt Gene Name: | TMBIM1 |
| UniProt Entry Name: | LFG3_HUMAN |
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