Cell Biology Antibodies 6

Anti-TKTL1 Antibody (CAB15337)

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SKU:
CAB15337
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TKTL1 Antibody
Antibody SKU:CAB15337
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human TKTL1 (NP_036385.3).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, 293T, A-549, BxPC-3, Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human TKTL1 (NP_036385.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RGTP SIED AESW HAKP MPRE RADA IIKL IESQ IQTS RNLD PQPP IEDS PEVN ITDV RMTS PPDY RVGD KIAT RKAC GLAL AKLG YANN RVVV LDGD TRYS TFSE IFNK EYPE RFIE CFMA E
Gene ID:8277
Uniprot:P51854
Cellular Location:Cytoplasm, Nucleus
Calculated MW:59kDa/61kDa/65kDa
Observed MW:65kDa
Synonyms:TKTL1, TKR, TKT2
Background:The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
NCBI Summary:The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
UniProt Code:P51854
NCBI GenInfo Identifier:122066426
NCBI Gene ID:8277
NCBI Accession:P51854.2
UniProt Secondary Accession:P51854,Q5TYJ8, Q5TYJ9, Q8TC75, A8K896,
UniProt Related Accession:P51854
Molecular Weight:– Da
NCBI Full Name:Transketolase-like protein 1
NCBI Synonym Full Names:transketolase like 1
NCBI Official Symbol:TKTL1  
NCBI Official Synonym Symbols:TKR; TKT2  
NCBI Protein Information:transketolase-like protein 1
UniProt Protein Name:Transketolase-like protein 1
UniProt Synonym Protein Names:Transketolase 2; TK 2; Transketolase-related protein
Protein Family:Transketolase-like protein
UniProt Gene Name:TKTL1  
Anti-TKTL1 Antibody (CAB15337)Western blot analysis of extracts of various cell lines, using TKTL1 antibody (CAB15337) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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