Cell Biology Antibodies 6

Anti-TKFC Antibody (CAB15421)

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SKU:
CAB15421
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TKFC Antibody
Antibody SKU:CAB15421
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, LO2, HeLa, Mouse heart, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VRRI KMAT ADEI VKLM LDHM TNTT NASH VPVQ PGSS VVMM VNNL GGLS FLEL GIIA DATV RSLE GRGV KIAR ALVG TFMS ALEM PGIS LTLL LVDE PLLK LIDA ETTA AAWP NVAA VSIT GRKR SRVA PAEP QEAP DSTA AGGS ASKR MALV LERV CSTL LGLE EHLN ALDR AAGD GDCG TTHS RAAR AIQE WLKE GPPP ASPA QLLS KLSV LLLE KMGG SSGA LYGL FLTA AAQP LKAK TSLP AWSA AMDA GLEA MQKY GKAA PGDR TMLD SLWA AGQE LQAW KSPG ADLL QVLT KAVK SAEA AAEA TKNM EAGA GRAS YISS ARLE QPDP GAVA AAAI LRAI LEVL QS
Gene ID:26007
Uniprot:Q3LXA3
Cellular Location:
Calculated MW:54kDa/58kDa
Observed MW:60kDa
Synonyms:TKFC, DAK, NET45
Background:This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4', 5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response (PubMed:17600090).
NCBI Summary:This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2017]
UniProt Code:Q3LXA3
NCBI GenInfo Identifier:20149621
NCBI Gene ID:26007
NCBI Accession:NP_056348.2
UniProt Secondary Accession:Q3LXA3,Q2L9C1, Q53EQ9, Q9BVA7, Q9H895,
UniProt Related Accession:Q3LXA3
Molecular Weight:54,793 Da
NCBI Full Name:triokinase/FMN cyclase isoform b
NCBI Synonym Full Names:triokinase and FMN cyclase
NCBI Official Symbol:TKFC  
NCBI Official Synonym Symbols:DAK; NET45  
NCBI Protein Information:triokinase/FMN cyclase
UniProt Protein Name:Triokinase/FMN cyclase
UniProt Synonym Protein Names:Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)Including the following 2 domains:ATP-dependent dihydroxyacetone kinase (EC:2.7.1.28, EC:2.7.1.29); DHA kinaseAlternative name(s):Glycerone kinase; Triokinase; Triose kinase
Protein Family:Dihydroxyacetone kinase
UniProt Gene Name:TKFC  
Anti-TKFC Antibody (CAB15421)Western blot analysis of extracts of various cell lines, using TKFC antibody (CAB15421). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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