KO Validated Antibodies 2

Anti-TIMM17A Antibody (CAB19917)[KO Validated]

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SKU:
CAB19917
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TIMM17A Antibody [KO Validated]
Antibody SKU:CAB19917
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human TIMM17A.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:293T
Immunogen:Recombinant protein of human TIMM17A.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10440
Uniprot:Q99595
Cellular Location:Mitochondrion inner membrane, Multi-pass membrane protein
Calculated MW:18kDa
Observed MW:16KDa
Anti-TIMM17A Antibody [KO Validated] (CAB19917)Western blot analysis of extracts from normal (control) and TIMM17A knockout (KO) 293T cells, using TIMM17A antibody (CAB19917) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Synonyms:TIMM17A, TIM17, TIM17A
Background:
UniProt Protein Function:TIMM17A: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family.
UniProt Protein Details:

Protein type:Mitochondrial; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: mitochondrial inner membrane; integral to mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex

Molecular Function:P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion

UniProt Code:Q99595
NCBI GenInfo Identifier:3219818
NCBI Gene ID:10440
NCBI Accession:Q99595.1
UniProt Secondary Accession:Q99595,Q9BWF5, B2RDM5,
UniProt Related Accession:Q99595
Molecular Weight:171
NCBI Full Name:Mitochondrial import inner membrane translocase subunit Tim17-A
NCBI Synonym Full Names:translocase of inner mitochondrial membrane 17 homolog A (yeast)
NCBI Official Symbol:TIMM17A  
NCBI Official Synonym Symbols:TIM17; TIM17A  
NCBI Protein Information:mitochondrial import inner membrane translocase subunit Tim17-A; preprotein translocase; mitochondrial inner membrane translocase; inner membrane preprotein translocase Tim17a
UniProt Protein Name:Mitochondrial import inner membrane translocase subunit Tim17-A
UniProt Synonym Protein Names:Inner membrane preprotein translocase Tim17a
Protein Family:Mitochondrial import inner membrane translocase
UniProt Gene Name:TIMM17A  
UniProt Entry Name:TI17A_HUMAN
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