Cell Biology Antibodies 4

Anti-TIMM17A Antibody (CAB13578)

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SKU:
CAB13578
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TIMM17A Antibody
Antibody SKU:CAB13578
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human TIMM17A (NP_006326.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:NCI-H460, HeLa, A-549, MCF7, HT-29, Mouse kidney, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human TIMM17A (NP_006326.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEEY AREP CPWR IVDD CGGA FTMG TIGG GIFQ AIKG FRNS PVGV NHRL RGSL TAIK TRAP QLGG SFAV WGGL FSMI DCSM VQVR GKED PWNS ITSG ALTG AILA ARNG PVAM VGSA AMGG ILLA LIEG AGIL LTRF ASAQ FPNG PQFA EDPS QLPS TQLP SSPF GDYR QYQ
Gene ID:10440
Uniprot:Q99595
Cellular Location:Mitochondrion inner membrane, Multi-pass membrane protein
Calculated MW:18kDa
Observed MW:18kDa
Synonyms:TIMM17A, TIM17, TIM17A
Background:
UniProt Protein Function:TIMM17A: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family.
UniProt Protein Details:

Protein type:Mitochondrial; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: mitochondrial inner membrane; integral to mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex

Molecular Function:P-P-bond-hydrolysis-driven protein transmembrane transporter activity

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion

UniProt Code:Q99595
NCBI GenInfo Identifier:3219818
NCBI Gene ID:10440
NCBI Accession:Q99595.1
UniProt Secondary Accession:Q99595,Q9BWF5, B2RDM5,
UniProt Related Accession:Q99595
Molecular Weight:171
NCBI Full Name:Mitochondrial import inner membrane translocase subunit Tim17-A
NCBI Synonym Full Names:translocase of inner mitochondrial membrane 17 homolog A (yeast)
NCBI Official Symbol:TIMM17A  
NCBI Official Synonym Symbols:TIM17; TIM17A  
NCBI Protein Information:mitochondrial import inner membrane translocase subunit Tim17-A; preprotein translocase; mitochondrial inner membrane translocase; inner membrane preprotein translocase Tim17a
UniProt Protein Name:Mitochondrial import inner membrane translocase subunit Tim17-A
UniProt Synonym Protein Names:Inner membrane preprotein translocase Tim17a
Protein Family:Mitochondrial import inner membrane translocase
UniProt Gene Name:TIMM17A  
UniProt Entry Name:TI17A_HUMAN
Anti-TIMM17A Antibody (CAB13578)Western blot analysis of extracts of various cell lines, using TIMM17A antibody (CAB13578) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-TIMM17A Antibody (CAB13578)Immunohistochemistry of paraffin-embedded human liver cancer using TIMM17A antibody (CAB13578) at dilution of 1:100 (40x lens).
Anti-TIMM17A Antibody (CAB13578)Immunofluorescence analysis of U2OS cells using TIMM17A antibody (CAB13578). Blue: DAPI for nuclear staining.
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