Cell Biology Antibodies 9
Anti-TIMM10 Antibody (CAB4626)
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- SKU:
- CAB4626
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TIMM10
- Synonyms:
- TIM10
- Synonyms:
- TIM10A
- Synonyms:
- TIMM10A
- Research Area:
- Cell Biology
Description
| Product Name: | TIMM10 Rabbit pAb |
| Product Code: | CAB4626 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | TIMM10, TIM10, TIM10A, TIMM10A |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TIMM10 (NP_036588.1). |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, LO2, HepG2, NCI-H460, Mouse brain, Mouse small intestine, Mouse liver, Mouse heart, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human TIMM10 (NP_036588.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDPL RAQQ LAAE LEVE MMAD MYNR MTSA CHRK CVPP HYKE AELS KGES VCLD RCVS KYLD IHER MGKK LTEL SMQD EELM KRVQ QSSG PA |
| Gene ID: | 26519 |
| Uniprot: | P62072 |
| Cellular Location: | Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein |
| Calculated MW: | 10kDa |
| Observed MW: | 12kDa |
| UniProt Protein Function: | TIMM10: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Belongs to the small Tim family. |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 11q12.1 Cellular Component: mitochondrial intermembrane space protein transporter complex; mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial inner membrane presequence translocase complex Molecular Function:protein binding; protein homodimerization activity; zinc ion binding; transporter activity; chaperone binding; protein transporter activity Biological Process: cellular protein metabolic process; sensory perception of sound; protein import into mitochondrial inner membrane; protein targeting to mitochondrion |
| NCBI Summary: | The mitochondrial protein encoded by this gene belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane, functioning as intermembrane space chaperones for the highly insoluble carrier proteins. [provided by RefSeq, Nov 2011] |
| UniProt Code: | P62072 |
| NCBI GenInfo Identifier: | 49065657 |
| NCBI Gene ID: | 26519 |
| NCBI Accession: | P62072.1 |
| UniProt Secondary Accession: | P62072,Q9WV99, Q9WVA0, Q9Y5J8, A8K136, |
| UniProt Related Accession: | P62072 |
| Molecular Weight: | 90 |
| NCBI Full Name: | Mitochondrial import inner membrane translocase subunit Tim10 |
| NCBI Synonym Full Names: | translocase of inner mitochondrial membrane 10 homolog (yeast) |
| NCBI Official Symbol: | TIMM10 |
| NCBI Official Synonym Symbols: | TIM10; TIM10A |
| NCBI Protein Information: | mitochondrial import inner membrane translocase subunit Tim10 |
| UniProt Protein Name: | Mitochondrial import inner membrane translocase subunit Tim10 |
| UniProt Gene Name: | TIMM10 |
| UniProt Entry Name: | TIM10_HUMAN |
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