Anti-TIGIT Antibody (CAB20350)
- SKU:
- CAB20350
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- VSIG9
- Synonyms:
- VSTM3
- Synonyms:
- WUCAM
Description
| Product Name: | TIGIT Rabbit pAb |
| Product Code: | CAB20350 |
| Size: | 50uL, 100uL |
| Synonyms: | VSIG9, VSTM3, WUCAM |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human TIGIT. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Human plasma, Mouse lung |
| Immunogen: | Recombinant protein of human TIGIT. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 201633 |
| Uniprot: | Q495A1 |
| Calculated MW: | 26kDa |
| Observed MW: | 30kDa |
| UniProt Protein Function: | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009] |
| UniProt Code: | Q495A1 |
| NCBI GenInfo Identifier: | 121943253 |
| NCBI Gene ID: | 201633 |
| NCBI Accession: | Q495A1.1 |
| UniProt Secondary Accession: | Q495A1,Q495A3, Q5JPD8, Q6MZS2, Q8N877 |
| UniProt Related Accession: | Q495A1 |
| Molecular Weight: | 18,432 Da |
| NCBI Full Name: | T-cell immunoreceptor with Ig and ITIM domains |
| NCBI Synonym Full Names: | T cell immunoreceptor with Ig and ITIM domains |
| NCBI Official Symbol: | TIGIT |
| NCBI Official Synonym Symbols: | VSIG9; VSTM3; WUCAM |
| NCBI Protein Information: | T-cell immunoreceptor with Ig and ITIM domains |
| UniProt Protein Name: | T-cell immunoreceptor with Ig and ITIM domains |
| UniProt Synonym Protein Names: | V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3 |
| Protein Family: | T-cell immunoreceptor with Ig and ITIM domains |
| UniProt Gene Name: | TIGIT |
| UniProt Entry Name: |
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