Cell Death Antibodies 2
Anti-TIAF1 Antibody (CAB7762)
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- SKU:
- CAB7762
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-TIAF1 Antibody |
| Antibody SKU: | CAB7762 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human TIAF1 (NP_004731.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | PC-3, 293T, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human TIAF1 (NP_004731.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSSP SSPF REQS FLCA AGDA GEES RVQV LKNE VRRG SPVL LGWV EQAY ADKC VCGP SAPP APTP PSLS QRVM CNDL FKVN PFQL QQFR ADPS TASL LLCP GGLD HKLN LRGK AWG |
| Gene ID: | 9220 |
| Uniprot: | O95411 |
| Cellular Location: | Nucleus |
| Calculated MW: | 12kDa |
| Observed MW: | 12kDa |
| Synonyms: | TIAF1, MAJN, SPR210 |
| Background: |
| UniProt Protein Function: | TIAF1: Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: nucleus Biological Process: I-kappaB kinase/NF-kappaB cascade; apoptosis; negative regulation of apoptosis |
| UniProt Code: | O95411 |
| NCBI GenInfo Identifier: | 17978509 |
| NCBI Gene ID: | 9220 |
| NCBI Accession: | NP_004731 |
| UniProt Secondary Accession: | O95411,Q6PEG2, A2RRE2, |
| UniProt Related Accession: | O95411 |
| Molecular Weight: | 12,414 Da |
| NCBI Full Name: | TGFB1-induced anti-apoptotic factor 1 |
| NCBI Synonym Full Names: | TGFB1-induced anti-apoptotic factor 1 |
| NCBI Official Symbol: | TIAF1 |
| NCBI Official Synonym Symbols: | MAJN; SPR210 |
| NCBI Protein Information: | TGFB1-induced anti-apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1; molecule associated with Jak-3 N-terminal; 12 kDa TGF-beta-1-induced antiapoptotic factor |
| UniProt Protein Name: | TGFB1-induced anti-apoptotic factor 1 |
| UniProt Synonym Protein Names: | 12 kDa TGF-beta-1-induced antiapoptotic factor |
| UniProt Gene Name: | TIAF1 |
| UniProt Entry Name: | TIAF1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TIAF1 Antibody (CAB7762) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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