Anti-Thyroid Peroxidase Antibody (CAB19547)
- SKU:
- CAB19547
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MSA
- Synonyms:
- TDH2A
- Synonyms:
- TPX
Description
| Product Name: | Thyroid Peroxidase Rabbit mAb |
| Product Code: | CAB19547 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MSA, TDH2A, TPX |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Thyroid Peroxidase |
| Applications: | IHC |
| Recommended Dilutions: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthesized peptide derived from human Thyroid Peroxidase |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7173 |
| Uniprot: | P07202 |
| Calculated MW: | 103kDa |
| UniProt Protein Function: | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4. |
| NCBI Summary: | This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] |
| UniProt Code: | P07202 |
| NCBI GenInfo Identifier: | 160281455 |
| NCBI Gene ID: | 7173 |
| NCBI Accession: | P07202.4 |
| UniProt Secondary Accession: | P07202,P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96 Q8NF97, Q8TCI9, |
| UniProt Related Accession: | P07202 |
| Molecular Weight: | 96,699 Da |
| NCBI Full Name: | Thyroid peroxidase |
| NCBI Synonym Full Names: | thyroid peroxidase |
| NCBI Official Symbol: | TPO |
| NCBI Official Synonym Symbols: | MSA; TPX; TDH2A |
| NCBI Protein Information: | thyroid peroxidase |
| UniProt Protein Name: | Thyroid peroxidase |
| Protein Family: | Thyroid peroxidase |
| UniProt Gene Name: | TPO |
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