Anti-Thyroglobulin Antibody (CAB3409)
- SKU:
- CAB3409
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AITD3
- Synonyms:
- TGN
- Research Area:
- Metabolism
Description
| Product Name: | Thyroglobulin Rabbit mAb |
| Product Code: | CAB3409 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AITD3, TGN |
| Applications: | IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Thyroglobulin |
| Applications: | IHC, IF |
| Recommended Dilutions: | IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthesized peptide derived from human Thyroglobulin |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7038 |
| Uniprot: | P01266 |
| Cellular Location: | Secreted |
| Calculated MW: | 305kDa |
| UniProt Protein Function: | Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). |
| NCBI Summary: | Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009] |
| UniProt Code: | P01266 |
| NCBI GenInfo Identifier: | 126302607 |
| NCBI Gene ID: | 7038 |
| NCBI Accession: | P01266.5 |
| UniProt Secondary Accession: | P01266,O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2 Q9UMZ0, Q9UNY3, |
| UniProt Related Accession: | P01266 |
| Molecular Weight: | 298,383 Da |
| NCBI Full Name: | Thyroglobulin |
| NCBI Synonym Full Names: | thyroglobulin |
| NCBI Official Symbol: | TG |
| NCBI Official Synonym Symbols: | TGN; AITD3 |
| NCBI Protein Information: | thyroglobulin |
| UniProt Protein Name: | Thyroglobulin |
| Protein Family: | Thyroglobulin |
| UniProt Gene Name: | TG |
Related Products
Anti-Thyroglobulin Antibody (CAB3407)
OverviewProduct Name:Thyroglobulin Rabbit mAbProduct Code:CAB3407Size:20uL, 50uL, 100uLSynonyms:AITD3, TGNApplications
