Immunology Antibodies 1
Anti-THEMIS2 Antibody (CAB15355)
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- SKU:
- CAB15355
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-THEMIS2 Antibody |
| Antibody SKU: | CAB15355 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THEMIS2 (NP_004839.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, MCF7, Mouse spleen |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human THEMIS2 (NP_004839.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEPV PLQD FVRA LDPA SLPR VLRV CSGV YFEG SIYE ISGN ECCL STGD LIKV TQVR LQKV VCEN PKTS QTME LAPN FQGY FTPL NTPQ SYET LEEL VSAT TQSS KQLP TCFM STHR IVTE GRVV TEDQ LLML EAVV MHLG IRSA RCVL GMEG QQVI LHLP LSQK GPFW TWEP SAPR TLLQ VLQD PALK DLVL TCPT LPWH SLIL RPQY EIQA IMHI FSSL RIAA TRSA AQTQ GEDL ARVH QGWL QYVQ QDSC PQEG PQAR |
| Gene ID: | 9473 |
| Uniprot: | Q5TEJ8 |
| Cellular Location: | |
| Calculated MW: | 13kDa/29kDa/50kDa/56kDa/57kDa/72kDa |
| Observed MW: | 72kDa |
| Synonyms: | THEMIS2, C1orf38, ICB-1 |
| Background: |
| UniProt Protein Function: | THEMIS2: May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production. Belongs to the themis family. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 1p35.3 Molecular Function:protein binding Biological Process: cell adhesion |
| UniProt Code: | Q5TEJ8 |
| NCBI GenInfo Identifier: | 73920021 |
| NCBI Gene ID: | 9473 |
| NCBI Accession: | Q5TEJ8.1 |
| UniProt Secondary Accession: | Q5TEJ8,O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6 Q9NS90, A2RTZ3, B4DZT9, B4DZY3, |
| UniProt Related Accession: | Q5TEJ8 |
| Molecular Weight: | 50,028 Da |
| NCBI Full Name: | Protein THEMIS2 |
| NCBI Synonym Full Names: | thymocyte selection associated family member 2 |
| NCBI Official Symbol: | THEMIS2 |
| NCBI Official Synonym Symbols: | ICB-1; C1orf38 |
| NCBI Protein Information: | protein THEMIS2 |
| UniProt Protein Name: | Protein THEMIS2 |
| UniProt Synonym Protein Names: | Induced by contact to basement membrane 1 protein; Protein ICB-1; Thymocyte-expressed molecule involved in selection protein 2 |
| Protein Family: | Protein |
| UniProt Gene Name: | THEMIS2 |
| UniProt Entry Name: | THMS2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using THEMIS2 antibody (CAB15355) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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