Cell Biology Antibodies 8
Anti-THBS3 Antibody (CAB3641)
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- SKU:
- CAB3641
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-THBS3 Antibody |
| Antibody SKU: | CAB3641 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 787-956 of human THBS3 (NP_009043.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse kidney, Mouse ovary |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 787-956 of human THBS3 (NP_009043.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TDDD YAGF LFSY QDSG RFYV VMWK QTEQ TYWQ ATPF RAVA QPGL QLKA VTSV SGPG EHLR NALW HTGH TPDQ VRLL WTDP RNVG WRDK TSYR WQLL HRPQ VGYI RVKL YEGP QLVA DSGV IIDT SMRG GRLG VFCF SQEN IIWS NLQY RCND TVPE DFEP FRRQ LLQG RV |
| Gene ID: | 7059 |
| Uniprot: | P49746 |
| Cellular Location: | |
| Calculated MW: | 91kDa/104kDa |
| Observed MW: | 104kDa |
| Synonyms: | THBS3, TSP3 |
| Background: | The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. |
| UniProt Protein Function: | THBS3: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Belongs to the thrombospondin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1q21 Cellular Component: perinuclear region of cytoplasm; extracellular region Molecular Function:heparin binding; calcium ion binding Biological Process: cell-matrix adhesion |
| NCBI Summary: | The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011] |
| UniProt Code: | P49746 |
| NCBI GenInfo Identifier: | 6005902 |
| NCBI Gene ID: | 7059 |
| NCBI Accession: | NP_009043.1 |
| UniProt Secondary Accession: | P49746,Q8WV34, B1AVR8, B4DQ20, |
| UniProt Related Accession: | P49746 |
| Molecular Weight: | 91,297 Da |
| NCBI Full Name: | thrombospondin-3 isoform 1 |
| NCBI Synonym Full Names: | thrombospondin 3 |
| NCBI Official Symbol: | THBS3 |
| NCBI Official Synonym Symbols: | TSP3 |
| NCBI Protein Information: | thrombospondin-3 |
| UniProt Protein Name: | Thrombospondin-3 |
| Protein Family: | Thrombospondin |
| UniProt Gene Name: | THBS3 |
| UniProt Entry Name: | TSP3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using THBS3 antibody (CAB3641) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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