Cell Biology Antibodies 5

Anti-THAP12 Antibody (CAB15085)

(No reviews yet) Write a Review
SKU:
CAB15085
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-THAP12 Antibody
Antibody SKU:CAB15085
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human THAP12 (NP_004696.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, mouse brain, rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human THAP12 (NP_004696.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPNF CAAP NCTR KSTQ SDLA FFRF PRDP ARCQ KWVE NCRR ADLE DKTP DQLN KHYR LCAK HFET SMIC RTSP YRTV LRDN AIPT IFDL TSHL NNPH SRHR KRIK ELSE DEIR TLKQ KKID ETSE QEQK HKET NNSN AQNP SEEE GEGQ DEDI LPLT LEEK ENKE YLKS LFEI LILM GKQN IPLD GHEA DEIP EGLF TPDN FQAL LECR INSG EEVL RKRF ETTA VNTL FCSK TQQR QMLE ICES CIRE ETLR EVRD SHFF SIIT DDVV DIAG EEHL PVLV RFVD ESHN LREE FIGF LPYE
Gene ID:5612
Uniprot:O43422
Cellular Location:
Calculated MW:56kDa/87kDa
Observed MW:52kDa
Synonyms:THAP12, DAP4, P52rIPK, PRKRIR, THAP0
Background:
UniProt Protein Function:PRKRIR: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR- inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Protein kinase, regulatory subunit; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q13.5

Cellular Component: nucleus

Molecular Function:protein dimerization activity; DNA binding; metal ion binding

Biological Process: negative regulation of cell proliferation; response to stress; signal transduction

UniProt Code:O43422
NCBI GenInfo Identifier:12643558
NCBI Gene ID:5612
NCBI Accession:O43422.2
UniProt Secondary Accession:O43422,Q9CUX1,
UniProt Related Accession:O43422
Molecular Weight:1137
NCBI Full Name:52 kDa repressor of the inhibitor of the protein kinase
NCBI Synonym Full Names:protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
NCBI Official Symbol:PRKRIR  
NCBI Official Synonym Symbols:DAP4; THAP0; THAP12; P52rIPK  
NCBI Protein Information:52 kDa repressor of the inhibitor of the protein kinase; THAP domain containing 12; death-associated protein 4; p58IPK-interacting protein; inhibitor of protein kinase PKR; THAP domain-containing protein 0; 58 kDa interferon-induced protein kinase-interac
UniProt Protein Name:52 kDa repressor of the inhibitor of the protein kinase
UniProt Synonym Protein Names:58 kDa interferon-induced protein kinase-interacting protein; p58IPK-interacting protein; Death-associated protein 4; THAP domain-containing protein 0
Protein Family:Dipeptidyl aminopeptidase
UniProt Gene Name:PRKRIR  
UniProt Entry Name:P52K_HUMAN
Anti-THAP12 Antibody (CAB15085)Western blot analysis of extracts of various cell lines, using THAP12 antibody (CAB15085) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products