| UniProt Protein Function: | THAP11: Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers. Belongs to the THAP11 family. Interacts (via coiled coil domain) with HCFC1. Protein type: DNA-binding Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: cytoplasm; intercellular bridge; nucleoplasm Molecular Function: DNA binding; protein binding; zinc ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96EK4 |
| NCBI GenInfo Identifier: | 209572685 |
| NCBI Gene ID: | 57215 |
| NCBI Accession: | Q96EK4.2 |
| UniProt Secondary Accession: | Q96EK4,O94795, A4UCT5, A8K002 |
| UniProt Related Accession: | Q96EK4 |
| Molecular Weight: | 34,455 Da |
| NCBI Full Name: | THAP domain-containing protein 11 |
| NCBI Synonym Full Names: | THAP domain containing 11 |
| NCBI Official Symbol: | THAP11 |
| NCBI Official Synonym Symbols: | RONIN; CTG-B43a; CTG-B45d; HRIHFB2206 |
| NCBI Protein Information: | THAP domain-containing protein 11 |
| UniProt Protein Name: | THAP domain-containing protein 11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | THAP domain-containing protein |
| UniProt Gene Name: | THAP11 |
| UniProt Entry Name: | THA11_HUMAN |
