ChIP Antibodies
Anti-THADA Antibody (CAB7129)
- SKU:
- CAB7129
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-THADA Antibody |
| Antibody SKU: | CAB7129 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1684-1953 of human THADA (NP_071348.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, HL-60, U-87MG, NCI-H460, Mouse lung, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1684-1953 of human THADA (NP_071348.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QLVI LSCE DHLP TESR LAVV EVLT STTP LFLT NPHP ILEL QDTL ALWK CVLT LLQS EEQA VRDA ATET VTTA MSQE NTCQ STEF AFCQ VDAS IALA LALA VLCD LLQQ WDQL APGL PILL GWLL GESD DLVA CVES MHQV EEDY LFEK AEVN FWAE TLIF VKYL CKHL FCLL SKSG WRPP SPEM LCHL QRMV SEQC HLLS QFFR ELPP AAEF VKTV EFTR LRIQ EERT LACL RLLA FLEG KEGE DTLV LSVW DSYA ESRQ LTLP RTEA AC |
| Gene ID: | 63892 |
| Uniprot: | Q6YHU6 |
| Cellular Location: | |
| Calculated MW: | 75kDa/100kDa/105kDa/183kDa/211kDa/219kDa |
| Observed MW: | 220kDa |
| Synonyms: | THADA, ARMC13, GITA |
| Background: | This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. |
| UniProt Protein Function: | THADA: Chromosomal aberrations involving THADA have been observed in benign thyroid adenomas. Translocation t(2;3)(p21;p25) and translocation t(2;7)(p21;p15); the sequences derived from chromosomes 3p25 and 7p15 do not appear to include a coding region and the fusion events probably result in truncated THADA proteins. Belongs to the THADA family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 2p21 |
| NCBI Summary: | This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016] |
| UniProt Code: | Q6YHU6 |
| NCBI GenInfo Identifier: | 74749519 |
| NCBI Gene ID: | 63892 |
| NCBI Accession: | Q6YHU6.1 |
| UniProt Related Accession: | Q6YHU6 |
| Molecular Weight: | |
| NCBI Full Name: | Thyroid adenoma-associated protein |
| NCBI Synonym Full Names: | THADA armadillo repeat containing |
| NCBI Official Symbol: | THADA |
| NCBI Official Synonym Symbols: | GITA; ARMC13 |
| NCBI Protein Information: | thyroid adenoma-associated protein |
| UniProt Protein Name: | Thyroid adenoma-associated protein |
| UniProt Synonym Protein Names: | Gene inducing thyroid adenomas protein |
| Protein Family: | Thyroid adenoma-associated protein |
| UniProt Gene Name: | THADA |
| UniProt Entry Name: | THADA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using THADA antibody (CAB7129) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of A549 cells using THADA antibody (CAB7129). Blue: DAPI for nuclear staining. |
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