Cell Biology Antibodies 7
Anti-TGOLN2 Antibody (CAB16707)
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- SKU:
- CAB16707
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TGOLN2 Antibody |
| Antibody SKU: | CAB16707 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic Peptide of human TGOLN2 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | mouse brain, rat brain |
| Immunogen: | A synthetic Peptide of human TGOLN2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10618 |
| Uniprot: | O43493 |
| Cellular Location: | Cell membrane, Golgi apparatus, Single-pass type I membrane protein, trans-Golgi network membrane |
| Calculated MW: | 29kDa/39kDa/45kDa/47kDa/51kDa |
| Observed MW: | 110kDa |
| Synonyms: | TGOLN2, TGN38, TGN46, TGN48, TGN51, TTGN2 |
| Background: | This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: clathrin coated vesicle membrane; endosome; Golgi apparatus; nucleoplasm; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle; transport vesicle Molecular Function:protein binding Biological Process: Golgi to endosome transport |
| NCBI Summary: | This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | O43493 |
| NCBI GenInfo Identifier: | 158962337 |
| NCBI Gene ID: | 10618 |
| NCBI Accession: | O43493.2 |
| UniProt Secondary Accession: | O43493,O15282, O43492, O43499, O43500, O43501, Q53G68 Q53GV2, B2R686, B8ZZ88, D6W5K3, F8WBK2, |
| UniProt Related Accession: | O43493 |
| Molecular Weight: | 29,541 Da |
| NCBI Full Name: | Trans-Golgi network integral membrane protein 2 |
| NCBI Synonym Full Names: | trans-golgi network protein 2 |
| NCBI Official Symbol: | TGOLN2 |
| NCBI Official Synonym Symbols: | TGN38; TGN46; TGN48; TGN51; TTGN2 |
| NCBI Protein Information: | trans-Golgi network integral membrane protein 2 |
| UniProt Protein Name: | Trans-Golgi network integral membrane protein 2 |
| UniProt Synonym Protein Names: | TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51 |
| Protein Family: | Trans-Golgi network integral membrane protein |
| UniProt Gene Name: | TGOLN2 |
 | Western blot analysis of extracts of various cell lines, using TGOLN2 antibody (CAB16707) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1min. |
 | Immunohistochemistry of paraffin-embedded Mouse testis using TGOLN2 Rabbit pAb (CAB16707) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Mouse testis using TGOLN2 Rabbit pAb (CAB16707) at dilution of 1:100 (20x lens). |
 | Immunohistochemistry of paraffin-embedded Human colon using TGOLN2 Rabbit pAb (CAB16707) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U-2 OS cells using TGOLN2 Rabbit pAb (CAB16707) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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