Description
| Product Name: | TGN46/TGOLN2 Rabbit mAb |
| Product Code: | CAB19618 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | TGN38, TGN46, TGN48, TGN51, TTGN2 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human TGN46/TGOLN2 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | HeLa |
| Immunogen: | A synthesized peptide derived from human TGN46/TGOLN2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10618 |
| Uniprot: | O43493 |
| Calculated MW: | 90kDa |
| Observed MW: | 90-100KDa |
| UniProt Protein Function: | TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: clathrin coated vesicle membrane; endosome; Golgi apparatus; nucleoplasm; plasma membrane; trans-Golgi network; trans-Golgi network transport vesicle; transport vesicle Molecular Function:protein binding Biological Process: Golgi to endosome transport |
| NCBI Summary: | This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | O43493 |
| NCBI GenInfo Identifier: | 158962337 |
| NCBI Gene ID: | 10618 |
| NCBI Accession: | O43493.2 |
| UniProt Secondary Accession: | O43493,O15282, O43492, O43499, O43500, O43501, Q53G68 Q53GV2, B2R686, B8ZZ88, D6W5K3, F8WBK2, |
| UniProt Related Accession: | O43493 |
| Molecular Weight: | 29,541 Da |
| NCBI Full Name: | Trans-Golgi network integral membrane protein 2 |
| NCBI Synonym Full Names: | trans-golgi network protein 2 |
| NCBI Official Symbol: | TGOLN2 |
| NCBI Official Synonym Symbols: | TGN38; TGN46; TGN48; TGN51; TTGN2 |
| NCBI Protein Information: | trans-Golgi network integral membrane protein 2 |
| UniProt Protein Name: | Trans-Golgi network integral membrane protein 2 |
| UniProt Synonym Protein Names: | TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51 |
| Protein Family: | Trans-Golgi network integral membrane protein |
| UniProt Gene Name: | TGOLN2 |