Description
Product Name: | TFF1/pS2 Rabbit mAb |
Product Code: | CAB6859 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 |
Applications: | WB, IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human TFF1/pS2 |
Applications: | WB, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human |
Positive Samples: | MCF7 |
Immunogen: | A synthesized peptide derived from human TFF1/pS2 |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 7031 |
Uniprot: | P04155 |
Calculated MW: | 9kDa |
Observed MW: | 13KDa |
UniProt Protein Function: | TFF1: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 21q22.3 Molecular Function:protein binding Biological Process: carbohydrate metabolic process |
NCBI Summary: | Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008] |
UniProt Code: | P04155 |
NCBI GenInfo Identifier: | 131127 |
NCBI Gene ID: | 7031 |
NCBI Accession: | P04155.1 |
UniProt Related Accession: | P04155 |
Molecular Weight: | 9,150 Da |
NCBI Full Name: | Trefoil factor 1 |
NCBI Synonym Full Names: | trefoil factor 1 |
NCBI Official Symbol: | TFF1 |
NCBI Official Synonym Symbols: | pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21 |
NCBI Protein Information: | trefoil factor 1 |
UniProt Protein Name: | Trefoil factor 1 |
UniProt Synonym Protein Names: | Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2 |
Protein Family: | Trefoil factor |
UniProt Gene Name: | TFF1 |
UniProt Entry Name: | TFF1_HUMAN |