Cell Biology Antibodies 11
Anti-TESK2 Antibody (CAB7460)
- SKU:
- CAB7460
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-TESK2 Antibody |
Antibody SKU: | CAB7460 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-571 of human TESK2 (NP_009101.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse liver, Mouse kidney |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-571 of human TESK2 (NP_009101.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | FVEI GKTL EEIL SRLQ EEEQ ERDR KLQP TARG LLEK APGV KRLS SLDD KIPH KSPC PRRT IWLS RSQS DIFS RKPP RTVS VLDP YYRP RDGA ARTP KVNP FSAR QDLM GGKI KFFD LPSK SVIS LVFD LDAP GPGT MPLA DWQE PLAP PIRR WRSL PGSP EFLH QEAC PFVG REES LSDG PPPR LSSL KYRV KEIP PFRA SALP AAQA HEAM DCSI LQEE NGFG SRPQ GTSP CPAG ASEE MEVE ERPA GSTP ATFS TSGI GLQT QGKQ DG |
Gene ID: | 10420 |
Uniprot: | Q96S53 |
Cellular Location: | Nucleus |
Calculated MW: | 60kDa/61kDa/63kDa |
Observed MW: | 64kDa |
Synonyms: | TESK2 |
Background: | This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | TESK2: a TKL kinase of the LISK family. Predominantly expressed in testis and prostate. The developmental expression pattern in the testis suggests an important role in meitoic stages and/or early stages of spermiogenesis. Three alternatively spliced isoforms have been described. |
UniProt Protein Details: | Protein type:Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.12.1; TKL group; LISK family; TESK subfamily Chromosomal Location of Human Ortholog: 1p32 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; protein kinase activity; protein serine/threonine kinase activity Biological Process: actin cytoskeleton organization and biogenesis; focal adhesion formation; protein amino acid phosphorylation; spermatogenesis |
NCBI Summary: | This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
UniProt Code: | Q96S53 |
NCBI GenInfo Identifier: | 25009462 |
NCBI Gene ID: | 10420 |
NCBI Accession: | Q96S53.1 |
UniProt Secondary Accession: | Q96S53,Q5T422, Q5T423, Q8N520, Q9Y3Q6, |
UniProt Related Accession: | Q96S53 |
Molecular Weight: | 60,332 Da |
NCBI Full Name: | Dual specificity testis-specific protein kinase 2 |
NCBI Synonym Full Names: | testis-specific kinase 2 |
NCBI Official Symbol: | TESK2 |
NCBI Protein Information: | dual specificity testis-specific protein kinase 2 |
UniProt Protein Name: | Dual specificity testis-specific protein kinase 2 |
UniProt Synonym Protein Names: | Testicular protein kinase 2 |
Protein Family: | Dual specificity testis-specific protein kinase |
UniProt Gene Name: | TESK2 |
UniProt Entry Name: | TESK2_HUMAN |
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