Cell Biology Antibodies 12

Anti-TEP1 Antibody (CAB9844)

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SKU:
CAB9844
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TEP1 Antibody
Antibody SKU:CAB9844
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2523-2627 of human TEP1 (NP_009041.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:DU145
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2523-2627 of human TEP1 (NP_009041.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TCRE SDAS MDSD ASMD SEPT PHLK TRQR RKIH SGSV TALH VLPE LLVT ASKD RDVK LWER PSMQ LLGL FRCE GSVS CLEP WLGA NSTL QLAV GDVQ GNVY FLNW E
Gene ID:7011
Uniprot:Q99973
Cellular Location:Chromosome, Nucleus, telomere
Calculated MW:289kDa/290kDa
Observed MW:290kDa
Synonyms:TEP1, TLP1, TP1, TROVE1, VAULT2, p240
Background:This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
NCBI Summary:This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Code:Q99973
NCBI GenInfo Identifier:21536371
NCBI Gene ID:7011
NCBI Accession:NP_009041.2
UniProt Secondary Accession:Q99973,A0AUV9,
UniProt Related Accession:Q99973
Molecular Weight:289,578 Da
NCBI Full Name:telomerase protein component 1 isoform 1
NCBI Synonym Full Names:telomerase associated protein 1
NCBI Official Symbol:TEP1  
NCBI Official Synonym Symbols:TP1; TLP1; p240; TROVE1; VAULT2  
NCBI Protein Information:telomerase protein component 1
UniProt Protein Name:Telomerase protein component 1
UniProt Synonym Protein Names:Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
UniProt Gene Name:TEP1  
Anti-TEP1 Polyclonal Antibody (CAB9844)Western blot analysis of extracts of DU145 cells, using TEP1 antibody (CAB9844) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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