Cell Death Antibodies 2
Anti-Tensin-4 Antibody (CAB8731)
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- SKU:
- CAB8731
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-Tensin-4 Antibody |
| Antibody SKU: | CAB8731 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-520 of human TNS4 (NP_116254.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HepG2, U-87MG, 22Rv1, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-520 of human TNS4 (NP_116254.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CPEP GSSP PQRT PGHQ NSVQ PGAA SPSN PCPA TRSN SQTL SDAP FTTC PEGP ARDM QPTM KFVM DTSK YWFK PNIT REQA IELL RKEE PGAF VIRD SSSY RGSF GLAL KVQE VPAS AQSR PGED SNDL IRHF LIES SAKG V |
| Gene ID: | 84951 |
| Uniprot: | Q8IZW8 |
| Cellular Location: | Cell junction, Cytoplasm, cytoskeleton, focal adhesion |
| Calculated MW: | 76kDa |
| Observed MW: | 77kDa |
| Synonyms: | TNS4, CTEN, PP14434, tensin-4 |
| Background: |
| UniProt Protein Function: | TNS4: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. May promote apoptosis, via its cleavage by caspase-3. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: focal adhesion Molecular Function:protein binding Biological Process: protein localization |
| UniProt Code: | Q8IZW8 |
| NCBI GenInfo Identifier: | 229463025 |
| NCBI Gene ID: | 84951 |
| NCBI Accession: | Q8IZW8.3 |
| UniProt Secondary Accession: | Q8IZW8,Q71RB7, Q8WV64, Q96JV4, A6NMJ7, |
| UniProt Related Accession: | Q8IZW8 |
| Molecular Weight: | 76,764 Da |
| NCBI Full Name: | Tensin-4 |
| NCBI Synonym Full Names: | tensin 4 |
| NCBI Official Symbol: | TNS4 |
| NCBI Official Synonym Symbols: | CTEN; PP14434 |
| NCBI Protein Information: | tensin-4 |
| UniProt Protein Name: | Tensin-4 |
| UniProt Synonym Protein Names: | C-terminal tensin-like protein |
| Protein Family: | Ctenidin |
| UniProt Gene Name: | TNS4 |
| UniProt Entry Name: | TENS4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TNS4 antibody (CAB8731) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
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