Name: Anti-TCF21 Antibody (CAB17451)
Brand: Epigenetics & Nuclear Signaling Antibodies 3
SKU: CAB17451
Availability: OutOfStock

Antibody Name:	Anti-TCF21 Antibody
Antibody SKU:	CAB17451
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human TCF21 (NP_003197.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	MCF7, BxPC-3, A-431

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human TCF21 (NP_003197.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EFVT SNES TEES SNCE NGSP QKGR GGLG KRRK APTK KSPL SGVS QEGK QVQR NAAN ARER ARMR VLSK AFS
Gene ID:	6943
Uniprot:	O43680
Cellular Location:
Calculated MW:	20kDa
Observed MW:	20kDa

Synonyms:	POD1, bHLHa23, TCF21
Background:	TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene.

UniProt Protein Function:	TCF21: Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.
UniProt Protein Details:	Protein type:Deacetylase; Motility/polarity/chemotaxis; DNA-binding; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: nucleus Molecular Function:androgen receptor binding; bHLH transcription factor binding; protein dimerization activity Biological Process: alveolus development; branchiomeric skeletal muscle development; embryonic digestive tract morphogenesis; epithelial cell differentiation; gland development; glomerulus development; kidney development; morphogenesis of a branching structure; negative regulation of transcription from RNA polymerase II promoter; palate development; positive regulation of transcription from RNA polymerase II promoter; reproductive structure development; Sertoli cell differentiation; sex determination; spleen development; ureteric bud branching; ureteric bud development; vasculature development
NCBI Summary:	TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	O43680
NCBI GenInfo Identifier:	15214319
NCBI Gene ID:	6943
NCBI Accession:	O43680.2
UniProt Secondary Accession:	O43680,O43545, Q6ICV0, Q9BZ14, E1P581,
UniProt Related Accession:	O43680
Molecular Weight:	19,715 Da
NCBI Full Name:	Transcription factor 21
NCBI Synonym Full Names:	transcription factor 21
NCBI Official Symbol:	TCF21
NCBI Official Synonym Symbols:	POD1; bHLHa23
NCBI Protein Information:	transcription factor 21
UniProt Protein Name:	Transcription factor 21
UniProt Synonym Protein Names:	Capsulin; Class A basic helix-loop-helix protein 23; bHLHa23; Epicardin; Podocyte-expressed 1; Pod-1
Protein Family:	Transcription factor
UniProt Gene Name:	TCF21
UniProt Entry Name:	TCF21_HUMAN

Western blot analysis of extracts of various cell lines, using TCF21 antibody (CAB17451) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5min.

ELISA Kits

Human TCF21 / Transcription factor 21 ELISA Kit

Human Transcription factor 21 (TCF21) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)