Cell Biology Antibodies 1

Anti-TBL3 Antibody (CAB10043)

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SKU:
CAB10043
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TBL3 Antibody
Antibody SKU:CAB10043
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 579-808 of human TBL3 (NP_006444.2).
Application:WB
Recommended Dilution:WB 1:1000 - 1:4000
Reactivity:Human, Mouse
Positive Samples:HeLa, SH-SY5Y, HL-60, MCF7
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 579-808 of human TBL3 (NP_006444.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LSSG SDGL VKLW TIKN NECV RTLD AHED KVWG LHCS RLDD HALT GASD SRVI LWKD VTEA EQAE EQAR QEEQ VVRQ QELD NLLH EKRY LRAL GLAI SLDR PHTV LTVI QAIR RDPE ACEK LEAT MLRL RRDQ KEAL LRFC VTWN TNSR HCHE AQAV LGVL LRRE APEE LLAY EGVR AALE ALLP YTER HFQR LSRT LQAA AFLD FLWH NMKL PVPA AAPT PWET HKGA LP
Gene ID:10607
Uniprot:Q12788
Cellular Location:Nucleus, nucleolus
Calculated MW:89kDa
Observed MW:110kDa
Synonyms:TBL3, SAZD, UTP13
Background:The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet.
NCBI Summary:The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]
UniProt Code:Q12788
NCBI GenInfo Identifier:19913369
NCBI Gene ID:10607
NCBI Accession:NP_006444.2
UniProt Secondary Accession:Q12788,Q59GD6, Q8IVB7, Q96A78,
UniProt Related Accession:Q12788
Molecular Weight:89,035 Da
NCBI Full Name:transducin beta-like protein 3
NCBI Synonym Full Names:transducin beta like 3
NCBI Official Symbol:TBL3  
NCBI Official Synonym Symbols:SAZD; UTP13  
NCBI Protein Information:transducin beta-like protein 3
UniProt Protein Name:Transducin beta-like protein 3
UniProt Synonym Protein Names:WD repeat-containing protein SAZD
Protein Family:Transducin beta-like protein
UniProt Gene Name:TBL3  
Anti-TBL3 Antibody (CAB10043)Western blot analysis of extracts of various cell lines, using TBL3 antibody (CAB10043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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