Cell Biology Antibodies 6

Anti-TBL2 Antibody (CAB15429)

(No reviews yet) Write a Review
SKU:
CAB15429
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TBL2 Antibody
Antibody SKU:CAB15429
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, 293T, HeLa, Mouse brain, Rat pancreas
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SNGK YLAT CADD RTIR IWST KDFL QREH RSMR ANVE LDHA TLVR FSPD CRAF IVWL ANGD TLRV FKMT KRED GGYT FTAT PEDF PKKH KAPV IDIG IANT GKFI MTAS SDTT VLIW SLKG QVLS TINT NQMN NTHA AVSP CGRF VASC GFTP DVKV WEVC FGKK GEFQ EVVR AFEL KGHS AAVH SFAF SNDS RRMA SVSK DGTW KLWD TDVE YKKK QDPY LLKT GRFE EAAG AAPC RLAL SPNA QVLA LASG SSIH LYNT RRGE KEEC FERV HGEC IANL SFDI TGRF LASC GDRA VRLF HNTP GHRA MVEE MQGH LKRA SNES TRQR LQQ
Gene ID:26608
Uniprot:Q9Y4P3
Cellular Location:
Calculated MW:49kDa
Observed MW:50kDa
Synonyms:TBL2, WBSCR13, WS-betaTRP
Background:This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
UniProt Protein Function:TBL2: TBL2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of TBL2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: endoplasmic reticulum; integral to endoplasmic reticulum membrane

Molecular Function:translation initiation factor binding; phosphoprotein binding; protein kinase binding

Biological Process: cellular response to glucose starvation; unfolded protein response

UniProt Code:Q9Y4P3
NCBI GenInfo Identifier:12643953
NCBI Gene ID:
NCBI Accession:Q9Y4P3.1
Molecular Weight:50kDa
NCBI Full Name:Transducin beta-like protein 2
UniProt Protein Name:Transducin beta-like protein 2
UniProt Synonym Protein Names:WS beta-transducin repeats protein; WS-betaTRP; Williams-Beuren syndrome chromosomal region 13 protein
Protein Family:Transducin beta-like protein
UniProt Gene Name:TBL2  
UniProt Entry Name:TBL2_HUMAN
Anti-TBL2 Antibody (CAB15429)Western blot analysis of extracts of various cell lines, using TBL2 antibody (CAB15429) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products