Cell Biology Antibodies 13
Anti-TAS2R7 Antibody (CAB17145)
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- SKU:
- CAB17145
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-TAS2R7 Antibody |
| Antibody SKU: | CAB17145 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human TAS2R7 (NP_076408.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human TAS2R7 (NP_076408.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SFFL LILS LRRH IRRM QLSA TGCR DPST EAHV RALK AVIS FLLL FIAY YLSF LIAT SSYF MPET ELAV IFGE SIAL IYPS SHSF ILIL GNNK LRHA SLKV IWKV MSIL KGRK FQQH KQI |
| Gene ID: | 50837 |
| Uniprot: | Q9NYW3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | TAS2R7, T2R7, TRB4 |
| Background: | This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. |
| UniProt Protein Function: | TAS2R7: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, T2R family Chromosomal Location of Human Ortholog: 12p13 Cellular Component: integral to membrane; plasma membrane Molecular Function:bitter taste receptor activity; taste receptor activity Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste |
| NCBI Summary: | This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NYW3 |
| NCBI GenInfo Identifier: | 29839663 |
| NCBI Gene ID: | 50837 |
| NCBI Accession: | Q9NYW3.1 |
| UniProt Secondary Accession: | Q9NYW3,Q645Y1, |
| UniProt Related Accession: | Q9NYW3 |
| Molecular Weight: | 36,550 Da |
| NCBI Full Name: | Taste receptor type 2 member 7 |
| NCBI Synonym Full Names: | taste 2 receptor member 7 |
| NCBI Official Symbol: | TAS2R7 |
| NCBI Official Synonym Symbols: | T2R7; TRB4 |
| NCBI Protein Information: | taste receptor type 2 member 7 |
| UniProt Protein Name: | Taste receptor type 2 member 7 |
| UniProt Synonym Protein Names: | Taste receptor family B member 4; TRB4 |
| Protein Family: | Taste receptor |
| UniProt Gene Name: | TAS2R7 |
| UniProt Entry Name: | TA2R7_HUMAN |
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