Cell Biology Antibodies 13

Anti-TAS2R14 Antibody (CAB17146)

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SKU:
CAB17146
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TAS2R14 Antibody
Antibody SKU:CAB17146
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R14 (NP_076411.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R14 (NP_076411.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IHIN ASIN GYRR NKTC SSDS SNFT RFSS LIVL TSTV FIFI PFTL SLAM FLLL IFSM WKHR KKMQ HTVK ISGD ASTK AHRG VKSV ITFF LLYA IFSL SFFI S
Gene ID:50840
Uniprot:Q9NYV8
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:TAS2R14, T2R14, TRB1
Background:This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
UniProt Protein Function:TAS2R14: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.
UniProt Protein Details:

Protein type:GPCR, T2R family; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to membrane; plasma membrane

Molecular Function:bitter taste receptor activity; taste receptor activity

Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; G-protein coupled receptor protein signaling pathway

NCBI Summary:This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NYV8
NCBI GenInfo Identifier:29839658
NCBI Gene ID:50840
NCBI Accession:Q9NYV8.1
UniProt Secondary Accession:Q9NYV8,Q645X3,
UniProt Related Accession:Q9NYV8
Molecular Weight:
NCBI Full Name:Taste receptor type 2 member 14
NCBI Synonym Full Names:taste 2 receptor member 14
NCBI Official Symbol:TAS2R14  
NCBI Official Synonym Symbols:TRB1; T2R14  
NCBI Protein Information:taste receptor type 2 member 14
UniProt Protein Name:Taste receptor type 2 member 14
UniProt Synonym Protein Names:Taste receptor family B member 1; TRB1
Protein Family:Taste receptor
UniProt Gene Name:TAS2R14  
UniProt Entry Name:T2R14_HUMAN
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