Metabolism Antibodies 1

Anti-TARS2 Antibody (CAB12853)

(No reviews yet) Write a Review
SKU:
CAB12853
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-TARS2 Antibody
Antibody SKU:CAB12853
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TARS2 (NP_079426.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:LO2, U-87MG, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TARS2 (NP_079426.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VNGE PYDL ERPL ETDS DLRF LTFD SPEG KAVF WHSS THVL GAAA EQFL GAVL CRGP STEY GFYH DFFL GKER TIRG SELP VLER ICQE LTAA ARPF RRLE ASRD QLRQ LFKD NPFK LHLI EEKV TGPT ATVY GCGT LVDL CQGP HLRH TGQI GGLK LLSN SSSL WRSS GAPE TLQR VSGI SFPT TELL RVWE AWRE EAEL RDHR RIGK EQEL FFFH ELSP GSCF FLPR GTRV YNAL VAFI RAEY AHRG FSEV KTPT LFST KLWE QSGH WEHY QEDM FAVQ PPGS DRPP SSQS DDST RHIT D
Gene ID:80222
Uniprot:Q9BW92
Cellular Location:Mitochondrion matrix
Calculated MW:66kDa/81kDa
Observed MW:81kDa
Synonyms:TARS2, COXPD21, TARSL1, thrRS
Background:This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.
UniProt Protein Function:TARS2: Belongs to the class-II aminoacyl-tRNA synthetase family.
UniProt Protein Details:

Protein type:Aminoacyl-tRNA synthetase; EC 6.1.1.3; Ligase; Mitochondrial; Translation; Translation regulation

Chromosomal Location of Human Ortholog: 1q21.2

Cellular Component: mitochondrion

Molecular Function:protein homodimerization activity; threonine-tRNA ligase activity

Disease: Combined Oxidative Phosphorylation Deficiency 21

NCBI Summary:This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4. [provided by RefSeq, Dec 2012]
UniProt Code:Q9BW92
NCBI GenInfo Identifier:74752395
NCBI Gene ID:80222
NCBI Accession:Q9BW92.1
UniProt Secondary Accession:Q9BW92,Q53GW7, Q96I50, Q9H9V2,
UniProt Related Accession:Q9BW92
Molecular Weight:81kDa
NCBI Full Name:Threonine--tRNA ligase, mitochondrial
NCBI Synonym Full Names:threonyl-tRNA synthetase 2, mitochondrial (putative)
NCBI Official Symbol:TARS2  
NCBI Official Synonym Symbols:thrRS; TARSL1; COXPD21  
NCBI Protein Information:threonine--tRNA ligase, mitochondrial
UniProt Protein Name:Threonine--tRNA ligase, mitochondrial
UniProt Synonym Protein Names:Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1
UniProt Gene Name:TARS2  
Anti-TARS2 Antibody (CAB12853)Western blot analysis of extracts of various cell lines, using TARS2 antibody (CAB12853) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products