Anti-Talin 2 Antibody (CAB19810)
- SKU:
- CAB19810
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ILWEQ
Description
| Product Name: | Talin 2 Rabbit mAb |
| Product Code: | CAB19810 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ILWEQ |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Talin 2 |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, NIH/3T3, Mouse testis, Rat testis |
| Immunogen: | A synthesized peptide derived from human Talin 2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 83660 |
| Uniprot: | Q9Y4G6 |
| Calculated MW: | 270kDa |
| Observed MW: | 272KDa |
| UniProt Protein Function: | talin 2: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: actin cytoskeleton; cytoplasm; fascia adherens; focal adhesion; intercellular junction; plasma membrane; ruffle; synapse Molecular Function:actin binding; actin filament binding; protein binding; structural constituent of cytoskeleton; structural molecule activity Biological Process: cell adhesion; cytoskeletal anchoring; intercellular junction assembly |
| NCBI Summary: | This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y4G6 |
| NCBI GenInfo Identifier: | 156938343 |
| NCBI Gene ID: | 83660 |
| NCBI Accession: | NP_055874.2 |
| UniProt Secondary Accession: | Q9Y4G6,A6NLB8, |
| UniProt Related Accession: | Q9Y4G6 |
| Molecular Weight: | 39.1 kDa |
| NCBI Full Name: | talin-2 |
| NCBI Synonym Full Names: | talin 2 |
| NCBI Official Symbol: | TLN2 |
| NCBI Official Synonym Symbols: | ILWEQ |
| NCBI Protein Information: | talin-2 |
| UniProt Protein Name: | Talin-2 |
| Protein Family: | Talin |
| UniProt Gene Name: | TLN2 |
| UniProt Entry Name: | TLN2_HUMAN |
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