Cell Biology Antibodies 18

Anti-TAF10 Antibody (CAB18387)

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SKU:
CAB18387
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-TAF10 Antibody
Antibody SKU:CAB18387
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human TAF10.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:
Immunogen:Recombinant protein of human TAF10.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6881
Uniprot:Q12962
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:TAF2A, TAF2H, TAFII30, TAF10
Background:
UniProt Protein Function:TAF10: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Belongs to the TAF10 family.
UniProt Protein Details:

Protein type:Transcription initiation complex; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 11p15.3

Cellular Component: cytoplasm; nucleoplasm; nucleus; PCAF complex; perinuclear region of cytoplasm; transcription factor TFIID complex

Molecular Function:enzyme binding; estrogen receptor binding; histone acetyltransferase activity; protein binding; transcription coactivator activity; transcription factor activity

Biological Process: histone deubiquitination; protein homooligomerization; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter

NCBI Summary:Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. [provided by RefSeq, Jul 2008]
UniProt Code:Q12962
NCBI GenInfo Identifier:3024688
NCBI Gene ID:6881
NCBI Accession:Q12962.1
UniProt Secondary Accession:Q12962,O00703, Q13175, Q6FH13,
UniProt Related Accession:Q12962
Molecular Weight:21,711 Da
NCBI Full Name:Transcription initiation factor TFIID subunit 10
NCBI Synonym Full Names:TATA-box binding protein associated factor 10
NCBI Official Symbol:TAF10  
NCBI Official Synonym Symbols:TAF2A; TAF2H; TAFII30  
NCBI Protein Information:transcription initiation factor TFIID subunit 10
UniProt Protein Name:Transcription initiation factor TFIID subunit 10
UniProt Synonym Protein Names:STAF28; Transcription initiation factor TFIID 30 kDa subunit; TAF(II)30; TAFII-30; TAFII30
Protein Family:Transcription initiation factor
UniProt Gene Name:TAF10  
UniProt Entry Name:TAF10_HUMAN
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