Anti-TACSTD2 Antibody (CAB8129)
- SKU:
- CAB8129
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TACSTD2
- Synonyms:
- EGP-1
- Synonyms:
- EGP1
- Synonyms:
- GA733-1
- Synonyms:
- GA7331
- Synonyms:
- GP50
- Synonyms:
- M1S1
- Synonyms:
- TROP2
Description
| Product Name: | TACSTD2 Rabbit pAb |
| Product Code: | CAB8129 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | TACSTD2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-270 of human TACSTD2 (NP_002344.2). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, A-431, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-270 of human TACSTD2 (NP_002344.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HTAA QDNC TCPT NKMT VCSP DGPG GRCQ CRAL GSGM AVDC STLT SKCL LLKA RMSA PKNA RTLV RPSE HALV DNDG LYDP DCDP EGRF KARQ CNQT SVCW CVNS VGVR RTDK GDLS LRCD ELVR THHI LIDL RHRP TAGA FNHS DLDA ELRR LFRE RYRL HPKF VAAV HYEQ PTIQ IELR QNTS QKAA GDVD IGDA AYYF ERDI KGES LFQG RGGL DLRV RGEP LQVE RTLI YYLD EIPP KFSM |
| Gene ID: | 4070 |
| Uniprot: | P09758 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 35kDa |
| Observed MW: | 37-50KDa |
| UniProt Protein Function: | TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p32 Cellular Component: basal plasma membrane; cytosol; extracellular space; integral to plasma membrane; lateral plasma membrane; membrane; nucleus Molecular Function:protein binding; receptor activity Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation Disease: Corneal Dystrophy, Gelatinous Drop-like |
| NCBI Summary: | This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009] |
| UniProt Code: | P09758 |
| NCBI GenInfo Identifier: | 160113102 |
| NCBI Gene ID: | 4070 |
| NCBI Accession: | P09758.3 |
| UniProt Secondary Accession: | P09758,Q15658, Q6FG48, Q7Z7Q4, Q96QD2, |
| UniProt Related Accession: | P09758 |
| Molecular Weight: | 35,709 Da |
| NCBI Full Name: | Tumor-associated calcium signal transducer 2 |
| NCBI Synonym Full Names: | tumor-associated calcium signal transducer 2 |
| NCBI Official Symbol: | TACSTD2 |
| NCBI Official Synonym Symbols: | EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1 |
| NCBI Protein Information: | tumor-associated calcium signal transducer 2 |
| UniProt Protein Name: | Tumor-associated calcium signal transducer 2 |
| UniProt Synonym Protein Names: | Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1 |
| Protein Family: | Tumor-associated calcium signal transducer |
| UniProt Gene Name: | TACSTD2 |
| UniProt Entry Name: | TACD2_HUMAN |
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