Anti-SYTL4 Antibody (CAB8273)

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SKU:
CAB8273
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
SYTL4
Synonyms:
SLP4

Description

Product Name:SYTL4 Rabbit pAb
Product Code:CAB8273
Size:20uL, 50uL, 100uL
Synonyms:SYTL4, SLP4
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-280 of human SYTL4 (NP_542775.2).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-280 of human SYTL4 (NP_542775.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GAKR GSQH YSDR TCAR CQES LGRL SPKT NTCR GCNH LVCR DCRI QESN GTWR CKVC AKEI ELKK ATGD WFYD QKVN RFAY RTGS EIIR MSLR HKPA VSKR ETVG QSLL HQTQ MGDI WPGR KIIQ ERQK EPSV LFEV PKLK SGKS ALEA ESES LDSF TADS DSTS RRDS LDKS GLFP EWKK MSAP KSQV EKET QPGG QNVV FVDE GEMI FKKN TRKI LRPS EYTK SVID LRP
Gene ID:94121
Uniprot:Q96C24
Cellular Location:Cell membrane, Cytoplasmic vesicle, Membrane, Peripheral membrane protein, secretory vesicle membrane
Calculated MW:39kDa/76kDa
Observed MW:Refer to figures
UniProt Protein Function:SYTL4: Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle Chromosomal Location of Human Ortholog: Xq21.33 Cellular Component: centrosome; cytoplasm; endosome; extrinsic to membrane; nucleoplasm; plasma membrane Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; neurexin binding; phospholipid binding; protein binding; syntaxin binding Biological Process: calcium ion-dependent exocytosis of neurotransmitter; positive regulation of exocytosis; positive regulation of protein secretion; regulation of calcium ion-dependent exocytosis; vesicle fusion
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]
UniProt Code:Q96C24
NCBI GenInfo Identifier:317373281
NCBI Gene ID:94121
NCBI Accession:Q96C24.2
UniProt Secondary Accession:Q96C24,Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1
UniProt Related Accession:Q96C24
Molecular Weight:39,813 Da
NCBI Full Name:Synaptotagmin-like protein 4
NCBI Synonym Full Names:synaptotagmin like 4
NCBI Official Symbol:SYTL4  
NCBI Official Synonym Symbols:SLP4  
NCBI Protein Information:synaptotagmin-like protein 4
UniProt Protein Name:Synaptotagmin-like protein 4
UniProt Synonym Protein Names:Exophilin-2; Granuphilin
Protein Family:Synaptotagmin-like protein
UniProt Gene Name:SYTL4  
UniProt Entry Name:SYTL4_HUMAN
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