Cell Biology Antibodies 13
Anti-SYT12 Antibody (CAB17242)
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- SKU:
- CAB17242
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SYT12 Antibody |
| Antibody SKU: | CAB17242 |
| Antibody Size: | 20uL, 50 uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-200 of human SYT12 (NP_001171351.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-200 of human SYT12 (NP_001171351.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KGSL SIED TFES ISEL GPLE LMGR ELDL APYG TLRK SQSA DSLN SISS VSNT FGQD FTLG QVEV SMEY DTAS HTLN VAVM QGKD LLER EEAS FESC FMRV SLLP DE |
| Gene ID: | 91683 |
| Uniprot: | Q8IV01 |
| Cellular Location: | |
| Calculated MW: | 46kDa |
| Observed MW: | Refer to figures |
| Synonyms: | SYT12, SYT11, sytXII |
| Background: | This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature. |
| NCBI Summary: | This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010] |
| UniProt Code: | Q8IV01 |
| NCBI GenInfo Identifier: | 29366828 |
| NCBI Gene ID: | 91683 |
| NCBI Accession: | NP_808878 |
| UniProt Related Accession: | Q8IV01 |
| Molecular Weight: | 46kDa |
| NCBI Full Name: | synaptotagmin-12 isoform a |
| NCBI Synonym Full Names: | synaptotagmin 12 |
| NCBI Official Symbol: | SYT12 |
| NCBI Official Synonym Symbols: | SYT11; sytXII |
| NCBI Protein Information: | synaptotagmin-12 |
| UniProt Protein Name: | Synaptotagmin-12 |
| UniProt Synonym Protein Names: | Synaptotagmin XII |
| Protein Family: | Synaptotagmin |
| UniProt Gene Name: | SYT12 |
| UniProt Entry Name: | SYT12_HUMAN |
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