Description
| Product Name: | Syntaxin 4 Rabbit mAb |
| Product Code: | CAB5996 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | STX4A, p35-2 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Syntaxin 4 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse lung, Rat brain |
| Immunogen: | A synthesized peptide derived from human Syntaxin 4 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6810 |
| Uniprot: | Q12846 |
| Calculated MW: | 34kDa |
| Observed MW: | 34KDa |
| UniProt Protein Function: | STX4: a protein of the syntaxin/epimorphin family. Contains 1 t-SNARE coiled-coil homology domain. Potentially involved in docking of synaptic vesicles at presynaptic active zones. Interacts with SNAP23 and SNAP25BP. Found in a complex with VAMP8 and SNAP23 in pancreas. |
| UniProt Protein Details: | Protein type:Vesicle; Membrane protein, integral Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: extracellular space; specific granule; cell surface; lateral loop; basolateral plasma membrane; integral to membrane; dendritic spine; trans-Golgi network; cytosol; SNARE complex; synaptic vesicle; membrane; perinuclear region of cytoplasm; lamellipodium; plasma membrane; vacuole; synapse; intracellular; endosome Molecular Function:sphingomyelin phosphodiesterase activator activity; SNAP receptor activity; SNARE binding; protein binding Biological Process: positive regulation of catalytic activity; platelet activation; positive regulation of cell adhesion; organelle fusion; positive regulation of eosinophil degranulation; positive regulation of chemotaxis; positive regulation of immunoglobulin secretion; synaptic vesicle fusion to presynaptic membrane; regulation of exocytosis; intracellular protein transport; response to hydroperoxide; vesicle docking; positive regulation of cell proliferation; post-Golgi vesicle-mediated transport; blood coagulation; positive regulation of cell migration |
| UniProt Code: | Q12846 |
| NCBI GenInfo Identifier: | 3041737 |
| NCBI Gene ID: | 6810 |
| NCBI Accession: | Q12846.2 |
| UniProt Secondary Accession: | Q12846,Q3SWZ3, P70452, Q08850, |
| UniProt Related Accession: | Q12846 |
| Molecular Weight: | 34180 |
| NCBI Full Name: | Syntaxin-4 |
| NCBI Synonym Full Names: | syntaxin 4 |
| NCBI Official Symbol: | STX4 |
| NCBI Official Synonym Symbols: | STX4A; p35-2 |
| NCBI Protein Information: | syntaxin-4 |
| UniProt Protein Name: | Syntaxin-4 |
| UniProt Synonym Protein Names: | Renal carcinoma antigen NY-REN-31 |
| UniProt Gene Name: | STX4 |
| UniProt Entry Name: | STX4_HUMAN |