Name: Anti-SULT1C2 Antibody (CAB8154)
Brand: Cell Biology Antibodies 11
SKU: CAB8154
Availability: OutOfStock

Antibody Name:	SULT1C2 Rabbit Polyclonal Antibody
Antibody SKU:	CAB8154
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SULT1C2 (NP_001047.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse
Positive Samples:	Mouse liver

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SULT1C2 (NP_001047.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MALT SDLG KQIK LKEV EGTL LQPA TVDN WSQI QSFE AKPD DLLI CTYP KAGT TWIQ EIVD MIEQ NGDV EKCQ RAII QHRH PFIE WARP PQPS GVEK AKAM PSPR ILKT HLST QLLP PSFW
Gene ID:	6819
Uniprot:	O00338
Cellular Location:	Cytoplasm
Calculated MW:	34kDa/35kDa
Observed MW:	35kDa

Synonyms:

SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2

Background:

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt Protein Function:	SULT1C1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Transferase; EC 2.8.2.- Chromosomal Location of Human Ortholog: 2q12.3 Cellular Component: cytoplasm; cytosol Molecular Function:aryl sulfotransferase activity; protein binding; sulfotransferase activity Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; amine metabolic process; sulfation
NCBI Summary:	Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	O00338
NCBI GenInfo Identifier:	29029530
NCBI Gene ID:	6819
NCBI Accession:	NP_789795
UniProt Secondary Accession:	O00338,Q53SG4, B2R813,
UniProt Related Accession:	O00338
Molecular Weight:	35,868 Da
NCBI Full Name:	sulfotransferase 1C2 isoform b
NCBI Synonym Full Names:	sulfotransferase family 1C member 2
NCBI Official Symbol:	SULT1C2
NCBI Official Synonym Symbols:	ST1C1; ST1C2; SULT1C1; humSULTC2
NCBI Protein Information:	sulfotransferase 1C2
UniProt Protein Name:	Sulfotransferase 1C2
UniProt Synonym Protein Names:	Sulfotransferase 1C1; SULT1C#1; humSULTC2
Protein Family:	Sulfotransferase
UniProt Gene Name:	SULT1C2
UniProt Entry Name:	ST1C2_HUMAN

Anti-SULT1C2 Polyclonal Antibody (CAB8154)

Western blot analysis of extracts of mouse liver, using SULT1C2 antibody (CAB8154) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45s.

Antibodies

SULT1C2 Antibody (PACO12579)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)