Cell Biology Antibodies 5
Anti-STYX Antibody (CAB15320)
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- SKU:
- CAB15320
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-STYX Antibody |
| Antibody SKU: | CAB15320 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human STYX (NP_660294.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-431, A-549, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human STYX (NP_660294.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEDV KLEF PSLP QCKE DAEE WTYP MRRE MQEI LPGL FLGP YSSA MKSK LPVL QKHG ITHI ICIR QNIE ANFI KPNF QQLF RYLV LDIA DNPV ENII RFFP MTKE FIDG SLQM GGKV LVHG NAGI SRSA AFVI AYIM ETFG MKYR DAFA YVQE RRFC INPN AGFV HQLQ EYEA IYLA KLTI QMMS PLQI ERSL SVHS GTTG SLKR THEE EDDF GTMQ VATA QNG |
| Gene ID: | 6815 |
| Uniprot: | Q8WUJ0 |
| Cellular Location: | Cytoplasm, Nucleus, cytosol |
| Calculated MW: | 25kDa |
| Observed MW: | 25kDa |
| Synonyms: | STYX |
| Background: | The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. |
| UniProt Protein Function: | Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). Seems to play a role in spermiogenesis. |
| NCBI Summary: | The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q8WUJ0 |
| NCBI GenInfo Identifier: | 21687043 |
| NCBI Gene ID: | 6815 |
| NCBI Accession: | NP_660294 |
| UniProt Secondary Accession: | Q8WUJ0,Q99850, B9EJG0, |
| UniProt Related Accession: | Q8WUJ0 |
| Molecular Weight: | 25.0 kDa (221aa), confirmed by MALDI-TOF |
| NCBI Full Name: | serine/threonine/tyrosine-interacting protein |
| NCBI Synonym Full Names: | serine/threonine/tyrosine interacting protein |
| NCBI Official Symbol: | STYX |
| NCBI Protein Information: | serine/threonine/tyrosine-interacting protein |
| UniProt Protein Name: | Serine/threonine/tyrosine-interacting protein |
| UniProt Synonym Protein Names: | Protein tyrosine phosphatase-like protein |
| Protein Family: | Serine/threonine/tyrosine-interacting protein |
| UniProt Gene Name: | STYX |
 | Western blot analysis of extracts of various cell lines, using STYX antibody (CAB15320) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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