Cell Biology Antibodies 12
Anti-STXBP4 Antibody (CAB8287)
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- SKU:
- CAB8287
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | STXBP4 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8287 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 344-553 of human STXBP4 (NP_848604.3). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549, HepG2, 293T, Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 344-553 of human STXBP4 (NP_848604.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EETR ALRS RIHL AEAA QRQA HGME MDYE EVIR LLEA KITE LKAQ LADY SDQN KESV QDLK KRIM VLDC QLRK SEMA RKTF EAST EKLL HFVE AIQE VFSD NSTP LSNL SERR AVLA SQTS LTPL GRNG RSIP ATLA LESK ELVK SVRA LLDM DCLP YGWE EAYT ADGI KYFI NHVT QTTS WIHP VMSV LNLS RSEE NEED CSRE LPNQ KS |
| Gene ID: | 252983 |
| Uniprot: | Q6ZWJ1 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 26kDa/61kDa |
| Observed MW: | 70kDa |
| Synonyms: | STXBP4, Synip |
| Background: |
| UniProt Protein Function: | Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose. |
| UniProt Code: | Q6ZWJ1 |
| NCBI GenInfo Identifier: | 63999048 |
| NCBI Gene ID: | 252983 |
| NCBI Accession: | NP_848604.3 |
| UniProt Secondary Accession: | Q6ZWJ1,Q8IVZ5, |
| UniProt Related Accession: | Q6ZWJ1 |
| Molecular Weight: | |
| NCBI Full Name: | syntaxin-binding protein 4 |
| NCBI Synonym Full Names: | syntaxin binding protein 4 |
| NCBI Official Symbol: | STXBP4 |
| NCBI Official Synonym Symbols: | Synip |
| NCBI Protein Information: | syntaxin-binding protein 4 |
| UniProt Protein Name: | Syntaxin-binding protein 4 |
| UniProt Synonym Protein Names: | Syntaxin 4-interacting protein; STX4-interacting protein; Synip |
| Protein Family: | Syntaxin-binding protein |
| UniProt Gene Name: | STXBP4 |
 | Western blot analysis of extracts of various cell lines, using STXBP4 antibody (CAB8287) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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