Cell Biology Antibodies 15

Anti-STX3 Antibody (CAB8152)

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SKU:
CAB8152
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody

Description

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Antibody Name:Anti-STX3 Antibody
Antibody SKU:CAB8152
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human STX3 (NP_004168.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human STX3 (NP_004168.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKDR LEQL KAKQ LTQD DDTD AVEI AIDN TAFM DEFF SEIE ETRL NIDK ISEH VEEA KKLY SIIL SAPI PEPK TKDD LEQL TTEI KKRA NNVR NKLK SMEK HIEE DEVR SSAD LRIR KSQH SVLS RKFV EVMT KYNE AQVD FRER SKGR IQRQ LEIT GKKT TDEE LEEM LESG NPAI FTSG IIDS QISK QALS EIEG RHKD IVRL ESSI KELH DMFM DIAM LVEN QGEM LDNI ELNV MHTV DHVE KARD ETKK AVKY QSQA RKK
Gene ID:6809
Uniprot:Q13277
Cellular Location:Membrane, Single-pass type IV membrane protein
Calculated MW:28kDa/32kDa/33kDa
Observed MW:Refer to figures
Synonyms:STX3, STX3A
Background:The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:STX3: Potentially involved in docking of synaptic vesicles at presynaptic active zones. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: apical plasma membrane; azurophil granule; growth cone; integral to membrane; intercellular junction; lamellipodium; neuron projection; plasma membrane; SNARE complex; specific granule; synaptic vesicle; vacuole

Molecular Function:arachidonic acid binding; protein binding; SNAP receptor activity; SNARE binding

Biological Process: intracellular protein transport; neurite development; positive regulation of cell adhesion; positive regulation of cell proliferation; positive regulation of chemotaxis; synaptic vesicle fusion to presynaptic membrane; vesicle docking

NCBI Summary:The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q13277
NCBI GenInfo Identifier:116242806
NCBI Gene ID:6809
NCBI Accession:Q13277.3
UniProt Secondary Accession:Q13277,O43750, O43751, Q15360, B4DME0,
UniProt Related Accession:Q13277
Molecular Weight:32,018 Da
NCBI Full Name:Syntaxin-3
NCBI Synonym Full Names:syntaxin 3
NCBI Official Symbol:STX3  
NCBI Official Synonym Symbols:STX3A  
NCBI Protein Information:syntaxin-3
UniProt Protein Name:Syntaxin-3
Protein Family:Syntaxin
UniProt Gene Name:STX3  
UniProt Entry Name:STX3_HUMAN
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